Azacitidine and Novalgin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azacitidine (azacitidine) and Novalgin (metamizole). Common drug interactions include neutropenia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Azacitidine and Novalgin. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Azacitidine?

Azacitidine has active ingredients of azacitidine. eHealthMe is studying from 17,184 Azacitidine users. Check the latest studies of Azacitidine.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

56 people who take Azacitidine and Novalgin together, and have interactions are studied.

Azacitidine and Novalgin drug interactions.

What are the common drug interactions of Azacitidine and Novalgin, by gender? *:

female:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Leukopenia (less number of white blood cells in blood)
  3. Diarrhoea
  4. Anaemia (lack of blood)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Nausea (feeling of having an urge to vomit)
  7. Fatigue (feeling of tiredness)
  8. Infection
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Hypertension (high blood pressure)

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Blood creatinine increased
  4. Cholecystitis (infection of gallbladder)
  5. Decreased appetite
  6. Hepatic infection fungal
  7. Nausea (feeling of having an urge to vomit)
  8. Oropharyngeal pain
  9. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Azacitidine and Novalgin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pancreas infection

40-49:

  1. Alanine aminotransferase increased
  2. Anaemia (lack of blood)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Infection
  5. Injection site reaction
  6. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  7. Platelet count decreased
  8. White blood cell count decreased

50-59:

  1. Interstitial lung disease
  2. C-reactive protein increased
  3. Infection
  4. Lung disorder (lung disease)

60+:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Anaemia (lack of blood)
  3. C-reactive protein increased
  4. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Depression
  8. Hypertension (high blood pressure)
  9. Infection
  10. Influenza

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 35 people, 62.50%
  2. Nausea (feeling of having an urge to vomit): 19 people, 33.93%
  3. High Blood Pressure: 19 people, 33.93%
  4. Constipation: 17 people, 30.36%
  5. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 16 people, 28.57%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 12 people, 21.43%
  7. Sleep Disorder: 10 people, 17.86%
  8. Back Pain: 8 people, 14.29%
  9. Insomnia (sleeplessness): 7 people, 12.50%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Azacitidine and Novalgin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azacitidine and Novalgin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azacitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Novalgin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azacitidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Novalgin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azacitidine and metamizole (the active ingredients of Azacitidine and Novalgin, respectively), and Azacitidine and Novalgin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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