Azactam and Ibu drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Azactam (aztreonam) and Ibu (ibuprofen). Common drug interactions include vomiting among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Azactam and Ibu. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Azactam?
Azactam has active ingredients of aztreonam. eHealthMe is studying from 1,044 Azactam users. Check the latest studies of Azactam.
What is Ibu?
Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.
18 people who take Azactam and Ibu together, and have interactions are studied.

What are the common drug interactions of Azactam and Ibu, by gender? *:
female:
- Vomiting
- Aspartate aminotransferase increased
- Deafness transitory (deafness temporary)
- Death
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Hepatitis (inflammation of the liver)
- Hidradenitis (chronic disease of a type of sweat gland)
- International normalised ratio increased
- Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
male:
- Pyrexia (fever)
- Alopecia (absence of hair from areas of the body)
- Chest pain
- Conjunctivitis (pink eye)
- Death
- Decreased appetite
- Depressed level of consciousness
- Depression
- Ear infection
- Failure to thrive (inadequate weight gain and physical growth in children)
What are the common drug interactions of Azactam and Ibu, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- International normalised ratio increased
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
- Aspartate aminotransferase increased
- Hepatitis (inflammation of the liver)
10-19:
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
- Nausea (feeling of having an urge to vomit)
- Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
- Pancreatitis acute (sudden inflammation of pancreas)
- Vomiting
- Hidradenitis (chronic disease of a type of sweat gland)
- Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
20-29:
- Hepatobiliary disease (diseases affect the liver and/or biliary tract)
30-39:
- Deafness transitory (deafness temporary)
40-49:
- Renal failure (kidney dysfunction)
- Dyspnoea (difficult or laboured respiration)
- Death
- Alopecia (absence of hair from areas of the body)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Asthma
- Attention deficit/hyperactivity disorder
- Axonal neuropathy (dysfunction of axon nerves)
- Blood immunoglobulin e increased
50-59:
- Renal failure (kidney dysfunction)
- Abscess limb (limb infection)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Chronic kidney disease
- Post-traumatic stress disorder
60+:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Neutropenia (an abnormally low number of neutrophils)
- Pyrexia (fever)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 33.33%
- Asthma: 3 people, 16.67%
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 3 people, 16.67%
- Swelling: 3 people, 16.67%
- High Blood Cholesterol: 3 people, 16.67%
- Infection: 3 people, 16.67%
- White Blood Cell Disorder: 2 people, 11.11%
- Fluid Overload (too much fluid in the blood): 2 people, 11.11%
- Gastrointestinal Toxicity (damage to digestive tract by any substance): 2 people, 11.11%
- Fungal Infection: 2 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Azactam and Ibu?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Azactam and Ibu:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Azactam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ibu:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Azactam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibu and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on aztreonam and ibuprofen (the active ingredients of Azactam and Ibu, respectively), and Azactam and Ibu (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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