Azelastine and Orenitram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azelastine (azelastine hydrochloride) and Orenitram (treprostinil). Common drug interactions include diarrhoea among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Azelastine and Orenitram. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Azelastine?

Azelastine has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 17,400 Azelastine users. Check the latest studies of Azelastine.

What is Orenitram?

Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.

On Jul, 16, 2026

18 people who take Azelastine and Orenitram together, and have interactions are studied.

Azelastine and Orenitram drug interactions.

What are the common drug interactions of Azelastine and Orenitram, by gender? *:

female:

Diarrhoea
Muscle spasms (muscle contraction)
Pain in extremity
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Palpitations (feelings or sensations that your heart is pounding or racing)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Blood pressure decreased
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Flushing (the warm, red condition of human skin)

male:

Constipation
Oedema peripheral (superficial swelling)

What are the common drug interactions of Azelastine and Orenitram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Asthenia (weakness)
Cough
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Nasopharyngitis (inflammation of the nasopharynx)
Upper respiratory tract infection

60+:

Cough
Headache (pain in head)
Vomiting
Abdominal discomfort
Alanine aminotransferase increased
Anxiety
Arthralgia (joint pain)
Aspartate aminotransferase increased
Blood bilirubin increased
Deafness unilateral

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 18 people, 100.00%
Back Pain: 2 people, 11.11%
Muscle Aches (muscle pain): 1 person, 5.56%
Hypokalemia (low potassium): 1 person, 5.56%
Hyperglycemia (high blood sugar): 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%
Enlarged Prostate: 1 person, 5.56%
Constipation: 1 person, 5.56%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Azelastine and Orenitram?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously