Azelastine and Roflumilast drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azelastine (azelastine hydrochloride) and Roflumilast (roflumilast). Common drug interactions include cellulitis among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Azelastine and Roflumilast. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Azelastine?

Azelastine has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 17,400 Azelastine users. Check the latest studies of Azelastine.

What is Roflumilast?

Roflumilast has active ingredients of roflumilast. eHealthMe is studying from 2,247 Roflumilast users. Check the latest studies of Roflumilast.

On Jul, 28, 2026

11 people who take Azelastine and Roflumilast together, and have interactions are studied.

Azelastine and Roflumilast drug interactions.

What are the common drug interactions of Azelastine and Roflumilast, by gender? *:

female:

Cellulitis (infection under the skin)
Anxiety
Asthenia (weakness)
Dizziness
Lipoma (a growth of fatty tissue that slowly develops just under your skin)
Pain
Scar
Sepsis (a severe blood infection that can lead to organ failure and death)
Catheter site haemorrhage (bleeding at catheter site)
Abdominal pain

male:

Death
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Epistaxis (bleed from the nose)
Haemorrhage subcutaneous (bleeding from skin)
Pneumonia

What are the common drug interactions of Azelastine and Roflumilast, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Swelling face
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Vomiting
Weight increased
Wheezing (a high-pitched whistling sound made while you breath)
Abdominal pain
Acute respiratory failure
Alanine aminotransferase increased

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Emotional distress
Epistaxis (bleed from the nose)
Exercise tolerance decreased
Haemorrhage subcutaneous (bleeding from skin)
Hip fracture
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
Illusion
Lower limb fracture

What are the existing conditions these people have? *

Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 9.09%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 9.09%
Pain: 1 person, 9.09%
Nausea (feeling of having an urge to vomit): 1 person, 9.09%
Multiple Allergies (allergy to multiple agents): 1 person, 9.09%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 1 person, 9.09%
Hiv Infection: 1 person, 9.09%
General Physical Health Deterioration (weak health status): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Azelastine and Roflumilast?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously