Azithromycin and Arthrotec drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Azithromycin (azithromycin) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include blood pressure diastolic decreased among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Arthrotec. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Azithromycin?
Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.
What is Arthrotec?
Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.
35 people who take Azithromycin and Arthrotec together, and have interactions are studied.

What are the common drug interactions of Azithromycin and Arthrotec, by gender? *:
female:
- Blood pressure diastolic decreased
- Blood pressure fluctuation
- Blood pressure systolic increased
- Bone disorder
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
- Contusion (a type of hematoma of tissue in which capillaries)
- Diarrhoea
- Drug ineffective
- Dysphonia (speech disorder attributable to a disorder of phonation)
male:
- Anxiety
- Constipation
- Balance disorder
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Diabetes mellitus inadequate control
- Diarrhoea
- Diastolic dysfunction
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Dizziness
- Drug diversion
What are the common drug interactions of Azithromycin and Arthrotec, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Gallbladder disorder
30-39:
- Anxiety
- Cholecystitis chronic (long lasting infection of gallbladder)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Emotional distress
- Gallbladder injury
- General physical health deterioration (weak health status)
- Injury
- Pulmonary embolism (blockage of the main artery of the lung)
40-49:
- Abdominal distension
- Abdominal pain
- Adenoma benign (non-cancerous tumour -secreting)
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Back pain
- Blood amylase increased
- Blood creatinine increased
- Blood glucose increased
- Blood potassium decreased
50-59:
- Constipation
- Decreased appetite
- Drug dependence
- Drug tolerance increased
- Dyspepsia (indigestion)
- Dyspnoea (difficult or laboured respiration)
- Hypersensitivity
- Insomnia (sleeplessness)
- Irritability
- Learning disability (difficulty in learning)
60+:
- Diarrhoea
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Pain in extremity
- Abdominal pain
- Blood pressure diastolic decreased
- Blood pressure fluctuation
- Blood pressure systolic increased
- Bone disorder
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 25.71%
- Pain: 8 people, 22.86%
- Depression: 8 people, 22.86%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 20.00%
- High Blood Pressure: 6 people, 17.14%
- Joint Pain: 5 people, 14.29%
- Pneumonia: 5 people, 14.29%
- High Blood Cholesterol: 5 people, 14.29%
- Muscle Spasms (muscle contraction): 4 people, 11.43%
- Infection: 3 people, 8.57%
* Approximation only. Some reports may have incomplete information.
Do you take Azithromycin and Arthrotec?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Azithromycin (40,716 reports)
- Arthrotec (11,986 reports)
Browse all drug interactions of Azithromycin and Arthrotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Azithromycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Arthrotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Azithromycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Arthrotec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on azithromycin and diclofenac sodium; misoprostol (the active ingredients of Azithromycin and Arthrotec, respectively), and Azithromycin and Arthrotec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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