Azithromycin and Bosentan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azithromycin (azithromycin) and Bosentan (bosentan). Common drug interactions include drug ineffective among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Bosentan. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Bosentan?

Bosentan has active ingredients of bosentan. eHealthMe is studying from 10,925 Bosentan users. Check the latest studies of Bosentan.

On Jul, 11, 2026

22 people who take Azithromycin and Bosentan together, and have interactions are studied.

Azithromycin and Bosentan drug interactions.

What are the common drug interactions of Azithromycin and Bosentan, by gender? *:

female:

Drug ineffective
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Oxygen saturation decreased
Pleural effusion (water on the lungs)
Pyrexia (fever)
Rhinovirus infection
Weight decreased
Agitation (state of anxiety or nervous excitement)
Bacterial infection
Body temperature increased

male:

Cardiac arrest
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Brain injury
Areflexia (absence of a reflex)
Drug clearance decreased
Hypotonia (low muscle tone)
Liver injury
Amylase increased
Bordetella infection (upper respiratory infection caused by the bordetella)
Diarrhoea

What are the common drug interactions of Azithromycin and Bosentan, by age (0-1 to 60+)? *:

0-1:

Cardiac arrest
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Bradycardia (abnormally slow heart action)
Drug ineffective
Haemodynamic instability (disturbances in the blood movement in our body)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)

2-9:

Amylase increased

10-19:

Drug ineffective
Renal failure acute (rapid kidney dysfunction)

20-29:

n/a

30-39:

n/a

40-49:

Cyst (a closed sac)
Device related infection
Dizziness
Furuncle (infection of the hair follicle)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hypotension (abnormally low blood pressure)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumonia
Proteus test positive

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 36.36%
Lower Respiratory Tract Infection: 8 people, 36.36%
Pain: 7 people, 31.82%
Agitation (state of anxiety or nervous excitement): 6 people, 27.27%
Staphylococcal Infection (an infection with staphylococcus bacteria): 4 people, 18.18%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 18.18%
Corynebacterium Infection (infection by corynebacterium (diphtheria)): 4 people, 18.18%
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 3 people, 13.64%
Hypotension (abnormally low blood pressure): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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