Azithromycin and Doxylamine succinate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azithromycin (azithromycin) and Doxylamine succinate (doxylamine succinate). Common drug interactions include drug ineffective among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Doxylamine succinate. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Doxylamine succinate?

Doxylamine succinate has active ingredients of doxylamine succinate. It is often used in insomnia. eHealthMe is studying from 2,851 Doxylamine succinate users. Check the latest studies of Doxylamine succinate.



On Jul, 13, 2026

16 people who take Azithromycin and Doxylamine succinate together, and have interactions are studied.

Azithromycin and Doxylamine succinate drug interactions.

What are the common drug interactions of Azithromycin and Doxylamine Succinate, by gender? *:

female:

  1. Drug ineffective
  2. Emotional distress
  3. Hyperhidrosis (abnormally increased sweating)
  4. Hyperreflexia (overactive or over responsive reflexes)
  5. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  6. Hypoxia (low oxygen in tissues)
  7. Maternal exposure during pregnancy (use of substance during pregnancy)
  8. Muscle contractions involuntary (uncontrolled muscle contraction)
  9. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  10. Myalgia (muscle pain)

male:

  1. Cardiac arrest
  2. Cryptorchism
  3. Electrocardiogram qt prolonged
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Azithromycin and Doxylamine Succinate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Electrocardiogram qt prolonged
  3. Overdose
  4. Pancreatitis (inflammation of pancreas)

30-39:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Hyperreflexia (overactive or over responsive reflexes)
  3. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  4. Hypoxia (low oxygen in tissues)
  5. Maternal exposure during pregnancy (use of substance during pregnancy)
  6. Muscle contractions involuntary (uncontrolled muscle contraction)
  7. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  8. Myalgia (muscle pain)
  9. Pyrexia (fever)
  10. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)

40-49:

  1. Cardiac arrest
  2. Electrocardiogram qt prolonged

50-59:

n/a

60+:

  1. Dry skin
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Pulmonary embolism (blockage of the main artery of the lung)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 2 people, 12.50%
  2. Vulvovaginal Candidiasis (vulvovaginal infection by fungi): 1 person, 6.25%
  3. Histiocytosis (a blood disease characterized by an abnormal multiplication of macrophages): 1 person, 6.25%
  4. Body Temperature Increased: 1 person, 6.25%
  5. Brain Neoplasm Malignant (brain cancer tumour): 1 person, 6.25%
  6. Cystic Fibrosis (disease of the secretary glands): 1 person, 6.25%
  7. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 1 person, 6.25%
  8. Depression: 1 person, 6.25%
  9. Dysmenorrhea (painful menstruation): 1 person, 6.25%
  10. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Azithromycin and Doxylamine succinate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azithromycin and Doxylamine succinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Doxylamine succinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxylamine succinate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin and doxylamine succinate (the active ingredients of Azithromycin and Doxylamine succinate, respectively), and Azithromycin and Doxylamine succinate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: