Azithromycin and Nubain drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azithromycin (azithromycin) and Nubain (nalbuphine hydrochloride). Common drug interactions include tooth extraction among females and bronchiolitis among males.

The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Nubain. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Nubain?

Nubain has active ingredients of nalbuphine hydrochloride. It is often used in pain. eHealthMe is studying from 1,749 Nubain users. Check the latest studies of Nubain.



On Jul, 10, 2026

12 people who take Azithromycin and Nubain together, and have interactions are studied.

Azithromycin and Nubain drug interactions.

What are the common drug interactions of Azithromycin and Nubain, by gender? *:

female:

  1. Tooth extraction
  2. Bone pain
  3. Osteonecrosis (death of bone)
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Wound dehiscence (a surgical incision reopens either internally or externally)
  6. Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Chronic kidney disease
  9. Eye pain
  10. Fear

male:

  1. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
  2. Hyperventilation
  3. Axillary vein thrombosis (formation of a blood clot in axillary vein)
  4. Cholecystitis chronic (long lasting infection of gallbladder)
  5. Cholesterosis (abnormal deposition of cholesterol in tissues)
  6. Conjunctivitis (pink eye)
  7. Conjunctivitis infective (infection of the conjunctiva)
  8. Death
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Azithromycin and Nubain, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Wound dehiscence (a surgical incision reopens either internally or externally)

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Fear
  5. Injury
  6. Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)

30-39:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Diabetic retinopathy (damage to the retina caused by complications of diabetes)

40-49:

  1. Abdominal pain upper
  2. Axillary vein thrombosis (formation of a blood clot in axillary vein)
  3. Cholecystitis chronic (long lasting infection of gallbladder)
  4. Cholesterosis (abnormal deposition of cholesterol in tissues)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Drug ineffective
  7. Impaired healing
  8. International normalised ratio increased
  9. Nausea (feeling of having an urge to vomit)
  10. Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)

50-59:

n/a

60+:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anxiety
  3. Constipation
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Cyst (a closed sac)
  6. Decreased interest
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Dehydration (dryness resulting from the removal of water)
  9. Depressed mood
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Inflammatory Bowel Disease: 2 people, 16.67%
  2. Thyroid Diseases: 1 person, 8.33%
  3. Dyspnea (difficult or laboured breathing): 1 person, 8.33%
  4. Bipolar Disorder (mood disorder): 1 person, 8.33%
  5. Birth Control: 1 person, 8.33%
  6. Blood Pressure Abnormal: 1 person, 8.33%
  7. Cardiac Disorder: 1 person, 8.33%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 8.33%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 8.33%
  10. Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Azithromycin and Nubain?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azithromycin and Nubain:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nubain:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nubain and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin and nalbuphine hydrochloride (the active ingredients of Azithromycin and Nubain, respectively), and Azithromycin and Nubain (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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