Azithromycin and Odefsey drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azithromycin (azithromycin) and Odefsey (emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate). Common drug interactions include arthralgia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Odefsey. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Odefsey?

Odefsey has active ingredients of emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 4,605 Odefsey users. Check the latest studies of Odefsey.

On Jul, 26, 2026

45 people who take Azithromycin and Odefsey together, and have interactions are studied.

Azithromycin and Odefsey drug interactions.

What are the common drug interactions of Azithromycin and Odefsey, by gender? *:

female:

Arthralgia (joint pain)
Blood creatinine increased
Bone loss
Chronic kidney disease
Death
Depressed mood
Dysstasia (difficulty in standing)
Epicondylitis (tennis elbow)
Exercise tolerance decreased
Mobility decreased (ability to move is reduced)

male:

Pain
Emotional distress
Wrist fracture
Depression
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Multiple fractures
Tooth loss
Blood creatinine increased
Mobility decreased (ability to move is reduced)

What are the common drug interactions of Azithromycin and Odefsey, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Fatigue (feeling of tiredness)
Glomerulosclerosis (a hardening of the glomerulus in the kidney)
Hypertension (high blood pressure)
Immune system disorder
Mobility decreased (ability to move is reduced)
Pain
Renal impairment (severely reduced kidney function)

30-39:

Renal failure (kidney dysfunction)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Mobility decreased (ability to move is reduced)
Renal cyst (kidney cyst)
Renal tubular necrosis (death of kidney tubules)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

40-49:

Wrist fracture
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Multiple fractures
Renal tubular disorder (disease of kidney tubules)
Rib fracture
Ankle fracture
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arteriovenous malformation
Back pain
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

50-59:

Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Osteoporosis (bones weak and more likely to break)
Chronic kidney disease
Renal impairment (severely reduced kidney function)
Bone density decreased
Depression
Exercise tolerance decreased

60+:

Emotional distress
Pain
Multiple fractures
Anaemia (lack of blood)
Asthenia (weakness)
Depression
Erectile dysfunction
Fall
Femur fracture
Fracture pain

What are the existing conditions these people have? *

Hypersensitivity: 5 people, 11.11%
Pain: 4 people, 8.89%
Infection: 4 people, 8.89%
Depression: 4 people, 8.89%
Bacterial Infection: 4 people, 8.89%
Nausea And Vomiting: 3 people, 6.67%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 6.67%
Herpes Zoster: 3 people, 6.67%
Cough: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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