Azithromycin and Tagamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azithromycin (azithromycin) and Tagamet (cimetidine). Common drug interactions include osteoarthritis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Tagamet. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.



On Jul, 06, 2026

80 people who take Azithromycin and Tagamet together, and have interactions are studied.

Azithromycin and Tagamet drug interactions.

What are the common drug interactions of Azithromycin and Tagamet, by gender? *:

female:

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  2. Pain
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Death
  5. Anxiety
  6. Bone disorder
  7. Calcium deficiency (lack of calcium)
  8. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  9. Chest pain
  10. Constipation

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Arthralgia (joint pain)
  4. Atelectasis (partial or complete collapse of the lung)
  5. Constipation
  6. Cough
  7. Deafness
  8. Decreased appetite
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Diarrhoea

What are the common drug interactions of Azithromycin and Tagamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Injury
  2. Pain in extremity
  3. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
  4. Arthralgia (joint pain)
  5. Chronic kidney disease
  6. Lower extremity mass (mass in lower legs)
  7. Phlebitis (inflammation of the walls of a vein)

40-49:

  1. Chronic kidney disease
  2. Coxsackie viral infection (coxsackie virus infection)
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Drug hypersensitivity
  5. Renal failure (kidney dysfunction)
  6. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

  1. Enterovirus test positive
  2. Fall
  3. Fibromyalgia (a long-term condition which causes pain all over the body)
  4. Foot deformity (functional disability of foot)
  5. Hallucination (an experience involving the perception of something not present)
  6. Headache (pain in head)
  7. Heart rate increased
  8. Human rhinovirus test positive
  9. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  10. Hypertension (high blood pressure)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Muscle spasms (muscle contraction)
  5. Nausea (feeling of having an urge to vomit)
  6. Pain
  7. Productive cough
  8. Adrenomegaly (enlarged adrenal glands)
  9. Adult respiratory distress syndrome (type of lung (pulmonary) failure)
  10. Arthralgia (joint pain)

What are the existing conditions these people have? *

  1. Pain: 49 people, 61.25%
  2. Infection: 44 people, 55.00%
  3. High Blood Cholesterol: 34 people, 42.50%
  4. High Blood Pressure: 32 people, 40.00%
  5. Blood Pressure Abnormal: 15 people, 18.75%
  6. Depression: 15 people, 18.75%
  7. Cardiac Disorder: 9 people, 11.25%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 11.25%
  9. Oedema (fluid collection in tissue): 8 people, 10.00%
  10. Indigestion: 8 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Azithromycin and Tagamet?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Azithromycin and Tagamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tagamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tagamet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin and cimetidine (the active ingredients of Azithromycin and Tagamet, respectively), and Azithromycin and Tagamet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: