Azopt and Metoclopramide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Azopt (brinzolamide) and Metoclopramide (metoclopramide hydrochloride). Common drug interactions include stress fracture among females and acne among males.
The phase IV clinical study analyzes what interactions people have when they take Azopt and Metoclopramide. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.
What is Azopt?
Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.
What is Metoclopramide?
Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.
42 people who take Azopt and Metoclopramide together, and have interactions are studied.

What are the common drug interactions of Azopt and Metoclopramide, by gender? *:
female:
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Ulna fracture (fracture inside bone)
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
- Urinary tract infection
- Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
- Vitamin d deficiency
- Wound infection
- Diarrhoea
- Chronic kidney disease
male:
- Acne (skin problems that cause pimples)
- Blood creatinine increased
- Hyperglycaemia (high blood sugar)
- Migraine (headache)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Pain
- Retinal vasculitis (a sight-threatening inflammatory eye condition that involves the retinal vessels)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Vertigo
- Weight increased
What are the common drug interactions of Azopt and Metoclopramide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pain
- Retinal vasculitis (a sight-threatening inflammatory eye condition that involves the retinal vessels)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Vertigo
- Weight increased
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Weight decreased
- Acne (skin problems that cause pimples)
- Blood creatinine increased
- Body temperature increased
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Diarrhoea
- Chronic kidney disease
- Contusion (a type of hematoma of tissue in which capillaries)
- Decreased appetite
- Electrolyte imbalance
- Enteritis (inflammation of the small intestine)
- Generalised oedema (swelling all over the body)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Platelet count decreased
- Starvation (a severe deficiency in caloric energy, nutrient, and vitamin intake)
What are the existing conditions these people have? *
- Pain: 13 people, 30.95%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 8 people, 19.05%
- Uveitis (inflammation of the uvea): 7 people, 16.67%
- Retinal Vasculitis (a sight-threatening inflammatory eye condition that involves the retinal vessels): 6 people, 14.29%
- High Blood Pressure: 6 people, 14.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 14.29%
- High Blood Cholesterol: 5 people, 11.90%
- Gastric Ulcer (stomach ulcer): 3 people, 7.14%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 7.14%
- Blood Uric Acid Increased: 3 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Azopt and Metoclopramide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Azopt (8,058 reports)
- Metoclopramide (81,263 reports)
Browse all drug interactions of Azopt and Metoclopramide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Azopt:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Metoclopramide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Azopt and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metoclopramide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on brinzolamide and metoclopramide hydrochloride (the active ingredients of Azopt and Metoclopramide, respectively), and Azopt and Metoclopramide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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