Azopt and Paroxetine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azopt (brinzolamide) and Paroxetine (paroxetine hydrochloride). Common drug interactions include hypoaesthesia among females and generalised oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Azopt and Paroxetine. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Azopt?

Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.

On Jul, 26, 2026

49 people who take Azopt and Paroxetine together, and have interactions are studied.

What are the common drug interactions of Azopt and Paroxetine, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Inappropriate antidiuretic hormone secretion
Injection site discolouration
Injection site haemorrhage (bleeding from injection site)
Iron deficiency anaemia
Long qt syndrome (disorder of the heart's electrical system)
Mass
Mouth injury
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

male:

Generalised oedema (swelling all over the body)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Fall
Fatigue (feeling of tiredness)
General physical health deterioration (weak health status)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Hypotension (abnormally low blood pressure)
Intraocular pressure increased
Muscle spasms (muscle contraction)
Myelodysplastic syndrome transformation (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged and gets changed into rapid progressing cancer)

What are the common drug interactions of Azopt and Paroxetine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Uveitis (inflammation of the uvea)
Drug ineffective
Encephalitis (inflammation of the brain)
Eye disorder
Mouth ulceration (mouth ulcers)
Abdominal discomfort
Arthralgia (joint pain)
Dry eye (lack of adequate tears)
Joint swelling
Blindness unilateral

30-39:

n/a

40-49:

n/a

50-59:

Cartilage atrophy (cartilage extra growth)
Hepatic steatosis (fatty liver disease)
Liver disorder (liver diseases)
Injection site pain
Nephrolithiasis (calculi in the kidneys)
Renal disorder (kidney disease)
Application site pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Injection site discolouration
Injection site haemorrhage (bleeding from injection site)

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Platelet count decreased
Dizziness
Dry mouth
Dyspnoea (difficult or laboured respiration)
Electrolyte imbalance
Fatigue (feeling of tiredness)
Generalised oedema (swelling all over the body)
Hypotension (abnormally low blood pressure)
Lip oedema (swelling of lip)

What are the existing conditions these people have? *

Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 22 people, 44.90%
Uveitis (inflammation of the uvea): 21 people, 42.86%
Depression: 9 people, 18.37%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 12.24%
Constipation: 6 people, 12.24%
High Blood Pressure: 5 people, 10.20%
Pain: 4 people, 8.16%
Vein Disorder: 3 people, 6.12%
Metastases To Peritoneum (cancer spreads to peritoneum): 3 people, 6.12%
Gastritis (inflammation of stomach): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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