Azopt and Zioptan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Azopt (brinzolamide) and Zioptan (tafluprost). Common drug interactions include headache among females and eye irritation among males.
The phase IV clinical study analyzes what interactions people have when they take Azopt and Zioptan. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Azopt?
Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.
What is Zioptan?
Zioptan has active ingredients of tafluprost. It is often used in glaucoma. eHealthMe is studying from 2,512 Zioptan users. Check the latest studies of Zioptan.
37 people who take Azopt and Zioptan together, and have interactions are studied.

What are the common drug interactions of Azopt and Zioptan, by gender? *:
female:
- Headache (pain in head)
- Lacrimation increased
- Lip swelling
- Nasopharyngitis (inflammation of the nasopharynx)
- Abdominal pain
- Affect lability (emotional incontinence)
- Agitation (state of anxiety or nervous excitement)
- Alopecia (absence of hair from areas of the body)
- Anger
- Asthenia (weakness)
male:
- Eye irritation
- Cardiac failure congestive
- Dizziness
- Documented hypersensitivity to administered drug
- Dry eye (lack of adequate tears)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Dyspnoea (difficult or laboured respiration)
- Eye discharge
- Eye pruritus (eye itching)
- Foreign body sensation in eyes (feeling of something in eye)
What are the common drug interactions of Azopt and Zioptan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Refraction disorder (an error in the focusing of light by the eye)
50-59:
- Anger
- Crying
- Affect lability (emotional incontinence)
- Agitation (state of anxiety or nervous excitement)
- Dermal cyst
- Diarrhoea
- Emotional disorder
- Eye irritation
- Feeling hot
- Hysterosalpingo-oophorectomy
60+:
- Cardiac failure congestive
- Eye irritation
- Back pain
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Cerebral haemorrhage (bleeding within the brain)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Cerebral thrombosis (blood clot in brain)
- Chest discomfort
- Chest pain
What are the existing conditions these people have? *
- Insomnia (sleeplessness): 3 people, 8.11%
- High Blood Pressure: 3 people, 8.11%
- High Blood Cholesterol: 3 people, 8.11%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 8.11%
- Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 2 people, 5.41%
- Type 2 Diabetes: 2 people, 5.41%
- Pain In Extremity: 2 people, 5.41%
- Intraocular Pressure Increased: 2 people, 5.41%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.41%
* Approximation only. Some reports may have incomplete information.
Do you take Azopt and Zioptan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Azopt and Zioptan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Azopt:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zioptan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Azopt and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zioptan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on brinzolamide and tafluprost (the active ingredients of Azopt and Zioptan, respectively), and Azopt and Zioptan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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