Azor and Simcor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azor (amlodipine besylate; olmesartan medoxomil) and Simcor (niacin; simvastatin). Common drug interactions include flushing among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Azor and Simcor. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Azor?

Azor has active ingredients of amlodipine besylate; olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 3,922 Azor users. Check the latest studies of Azor.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

On Jul, 10, 2026

48 people who take Azor and Simcor together, and have interactions are studied.

What are the common drug interactions of Azor and Simcor, by gender? *:

female:

Flushing (the warm, red condition of human skin)
Myalgia (muscle pain)
Feeling hot
Muscle spasms (muscle contraction)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Burning sensation
Arthralgia (joint pain)
Back pain
Complications of transplanted kidney

male:

Flushing (the warm, red condition of human skin)
Pruritus (severe itching of the skin)
Renal failure acute (rapid kidney dysfunction)
Swelling
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Dyspnoea (difficult or laboured respiration)
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Generalised erythema (redness of the skin all over the body)
Abnormal dreams
Blood glucose increased

What are the common drug interactions of Azor and Simcor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Burning sensation
Flushing (the warm, red condition of human skin)
Dizziness
Heart rate increased
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

Flushing (the warm, red condition of human skin)
Pruritus (severe itching of the skin)
Feeling hot
Hot flush (sudden feelings of heat)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Burning sensation
Dyspnoea (difficult or laboured respiration)
Generalised erythema (redness of the skin all over the body)
Insomnia (sleeplessness)
Myalgia (muscle pain)

60+:

Flushing (the warm, red condition of human skin)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Injection site urticaria (rash of round, red welts on the skin at injection site)
Intervertebral disc disorder (spinal disc disorder)
Knee arthroplasty
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)

What are the existing conditions these people have? *

High Density Lipoprotein Decreased: 9 people, 18.75%
Low Density Lipoprotein Increased (cholesterol increased in blood): 7 people, 14.58%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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