B12 and Dacogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take B12 (cobalamin) and Dacogen (decitabine). Common drug interactions include death among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take B12 and Dacogen. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,894 B12 users. Check the latest studies of B12.

What is Dacogen?

Dacogen has active ingredients of decitabine. eHealthMe is studying from 1,541 Dacogen users. Check the latest studies of Dacogen.

On Jul, 09, 2026

30 people who take B12 and Dacogen together, and have interactions are studied.

What are the common drug interactions of B12 and Dacogen, by gender? *:

female:

Death
Abdominal discomfort
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Blood disorder
Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
Drug ineffective
Hellp syndrome (life-threatening pregnancy complication)
Hospitalisation
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Vomiting

male:

Haemoglobin decreased
Platelet count decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Discomfort
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General physical health deterioration (weak health status)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hospitalisation

What are the common drug interactions of B12 and Dacogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Death

60+:

Death
White blood cell count decreased
Discomfort
Drug ineffective
Fall
Febrile neutropenia (fever with reduced white blood cells)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General physical health deterioration (weak health status)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hellp syndrome (life-threatening pregnancy complication)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 16 people, 53.33%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 8 people, 26.67%
Nausea (feeling of having an urge to vomit): 4 people, 13.33%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 10.00%
Leukaemia (blood or bone marrow cancer): 3 people, 10.00%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 10.00%
High Blood Pressure: 3 people, 10.00%
Essential Thrombocythaemia (chronic blood cancer): 3 people, 10.00%
Pain: 2 people, 6.67%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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