B12 and Lynparza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take B12 (cobalamin) and Lynparza (olaparib). Common drug interactions include sneezing among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take B12 and Lynparza. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,897 B12 users. Check the latest studies of B12.

What is Lynparza?

Lynparza has active ingredients of olaparib. eHealthMe is studying from 12,322 Lynparza users. Check the latest studies of Lynparza.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

66 people who take B12 and Lynparza together, and have interactions are studied.

What are the common drug interactions of B12 and Lynparza, by gender? *:

female:

Sneezing
Thrombocytopenia (decrease of platelets in blood)
Abdominal distension
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Cardiovascular disorder (heart diseases)
Chronic respiratory failure
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Dehydration (dryness resulting from the removal of water)
Dementia (madness)
Dizziness postural

male:

Asthenia (weakness)
Death
Blood iron decreased
Cerebral haemorrhage (bleeding within the brain)
Decreased appetite
Gait disturbance
Haemoglobin decreased
Hypokinesia (decreased bodily movement)
Insomnia (sleeplessness)
Iron deficiency

What are the common drug interactions of B12 and Lynparza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Malignant neoplasm progression (cancer tumour came back)
Metastases to liver (cancer spreads to liver)
Metastases to lung (cancer spreads to lung)

50-59:

Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Urine ketone body present
Vomiting
White blood cell count increased
Blood glucose increased
Constipation
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Neuropathy peripheral (surface nerve damage)
Ovarian epithelial cancer (cancer that begins in the cells on the surface of the ovary)

60+:

Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Full blood count decreased
Gait disturbance
Hypersensitivity
Malaise (a feeling of general discomfort or uneasiness)
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Carbohydrate antigen 125 increased
Constipation

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 36 people, 54.55%
Nausea (feeling of having an urge to vomit): 6 people, 9.09%
High Blood Cholesterol: 6 people, 9.09%
Prostate Cancer: 5 people, 7.58%
Breast Cancer Female: 5 people, 7.58%
Stress And Anxiety: 4 people, 6.06%
Sleep Disorder: 4 people, 6.06%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 6.06%
Pain: 4 people, 6.06%
High Blood Pressure: 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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