B12 and Sitagliptin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take B12 (cobalamin) and Sitagliptin (sitagliptin). Common drug interactions include diarrhoea among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take B12 and Sitagliptin. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,894 B12 users. Check the latest studies of B12.

What is Sitagliptin?

Sitagliptin has active ingredients of sitagliptin. eHealthMe is studying from 3,933 Sitagliptin users. Check the latest studies of Sitagliptin.

On Jul, 07, 2026

78 people who take B12 and Sitagliptin together, and have interactions are studied.

What are the common drug interactions of B12 and Sitagliptin, by gender? *:

female:

Diarrhoea
Anaemia (lack of blood)
Fall
Urinary tract infection
Hyperglycaemia (high blood sugar)
Skin lesion
Blood pressure systolic increased
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Injection site mass

male:

Death
Dyspnoea (difficult or laboured respiration)
Blood pressure systolic increased
Blood urine present
C-reactive protein increased
Crystal urine present
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Gait disturbance
Glucose urine present
Haemoglobin decreased

What are the common drug interactions of B12 and Sitagliptin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Vomiting
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Fracture
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Retching (strong involuntary effort to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

n/a

50-59:

Affect lability (emotional incontinence)
Alopecia (absence of hair from areas of the body)
Anogenital warts
Anxiety
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Bone pain
Burning sensation

60+:

Hypertension (high blood pressure)
Diabetes mellitus inadequate control
Exercise tolerance decreased
Mobility decreased (ability to move is reduced)
Abdominal discomfort
Urinary tract infection
Anaemia (lack of blood)
Fall
Blood pressure systolic increased
Diarrhoea

What are the existing conditions these people have? *

Diabetes: 32 people, 41.03%
Pain: 30 people, 38.46%
High Blood Pressure: 27 people, 34.62%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 26 people, 33.33%
Osteoporosis (bones weak and more likely to break): 25 people, 32.05%
Restless Leg Syndrome (a powerful urge to move your legs): 25 people, 32.05%
Psoriasis (immune-mediated disease that affects the skin): 25 people, 32.05%
Oedema Peripheral (superficial swelling): 25 people, 32.05%
Indigestion: 24 people, 30.77%
Wheezing (a high-pitched whistling sound made while you breath): 21 people, 26.92%

* Approximation only. Some reports may have incomplete information.

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