B12 and Talwin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take B12 (cobalamin) and Talwin (pentazocine lactate). Common drug interactions include malaise among females.

The phase IV clinical study analyzes what interactions people have when they take B12 and Talwin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,881 B12 users. Check the latest studies of B12.

What is Talwin?

Talwin has active ingredients of pentazocine lactate. It is often used in pain. eHealthMe is studying from 893 Talwin users. Check the latest studies of Talwin.

On Nov, 30, 2025

11 people who take B12 and Talwin together, and have interactions are studied.

What are the common drug interactions of B12 and Talwin, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Contusion (a type of hematoma of tissue in which capillaries)
Anaemia (lack of blood)
Blood creatinine increased
Blood iron increased
Blood potassium decreased
Blood pressure decreased
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Depressed mood

male:

n/a

What are the common drug interactions of B12 and Talwin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dysuria (painful or difficult urination)
Abdominal pain lower
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Blood creatinine increased
Blood iron increased
Blood potassium decreased
Blood pressure decreased
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite

40-49:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Depression
Drug effect decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Intestinal obstruction
Joint injury
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)

50-59:

Abdominal pain
Constipation
Diarrhoea
Disease progression

60+:

Joint injury
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Osteonecrosis of jaw (death of bone of jaw)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Contusion (a type of hematoma of tissue in which capillaries)
Drug effect decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 27.27%
Gastrointestinal Stoma Complication (complication of an opening surgically made in digestive tract): 3 people, 27.27%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 18.18%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 18.18%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 1 person, 9.09%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 9.09%
Diarrhea: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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