Baclofen and Aggrenox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Aggrenox (aspirin; dipyridamole). Common drug interactions include asthenia among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Aggrenox. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Aggrenox?

Aggrenox has active ingredients of aspirin; dipyridamole. It is often used in stroke. eHealthMe is studying from 7,654 Aggrenox users. Check the latest studies of Aggrenox.



On Jul, 29, 2026

96 people who take Baclofen and Aggrenox together, and have interactions are studied.

Baclofen and Aggrenox drug interactions.

What are the common drug interactions of Baclofen and Aggrenox, by gender? *:

female:

  1. Asthenia (weakness)
  2. Back pain
  3. Blood creatinine increased
  4. Confusional state
  5. Cough
  6. Dehydration (dryness resulting from the removal of water)
  7. Diarrhoea
  8. Dizziness
  9. Drug ineffective
  10. Drug toxicity

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pain
  3. Neck pain
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Anxiety
  6. Asthenia (weakness)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Clumsiness (a lack of coordination or elegance)
  9. Constipation
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the common drug interactions of Baclofen and Aggrenox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal discomfort
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Loss of consciousness
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Regurgitation (expulsion of material)
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

40-49:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  5. Thirst
  6. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  9. Back pain
  10. Blood magnesium decreased

50-59:

  1. Pain in extremity
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
  5. Arteriovenous fistula
  6. Blood pressure diastolic decreased
  7. Blood pressure diastolic increased
  8. Blood pressure systolic increased
  9. Bradycardia (abnormally slow heart action)
  10. Cellulitis (infection under the skin)

60+:

  1. Chronic kidney disease
  2. Mitral valve stenosis (narrowing of mitral valve)
  3. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  4. Headache (pain in head)
  5. Incision site pain
  6. Myalgia (muscle pain)
  7. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
  8. Peripheral swelling
  9. Procedural pain
  10. Blood creatinine increased

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 20 people, 20.83%
  2. Depression: 18 people, 18.75%
  3. High Blood Cholesterol: 18 people, 18.75%
  4. High Blood Pressure: 17 people, 17.71%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 16.67%
  6. Back Pain: 15 people, 15.62%
  7. Pain: 15 people, 15.62%
  8. Diabetes: 14 people, 14.58%
  9. Infection: 11 people, 11.46%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 10.42%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and Aggrenox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Aggrenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aggrenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aggrenox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and aspirin; dipyridamole (the active ingredients of Baclofen and Aggrenox, respectively), and Baclofen and Aggrenox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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