Baclofen and Durezol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Durezol (difluprednate). Common drug interactions include memory impairment among females and glossodynia among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Durezol. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Durezol?

Durezol has active ingredients of difluprednate. It is often used in uveitis. eHealthMe is studying from 3,441 Durezol users. Check the latest studies of Durezol.



On Jul, 06, 2026

46 people who take Baclofen and Durezol together, and have interactions are studied.

Baclofen and Durezol drug interactions.

What are the common drug interactions of Baclofen and Durezol, by gender? *:

female:

  1. Memory impairment
  2. Chronic kidney disease
  3. Disturbance in attention
  4. Gait disturbance
  5. Abnormal behaviour
  6. Renal failure (kidney dysfunction)
  7. Alopecia (absence of hair from areas of the body)
  8. Depression
  9. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  10. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

male:

  1. Glossodynia (a burning or painful sensation in the tongue)
  2. Dry mouth
  3. Cardiac failure congestive
  4. Cardiovascular disorder (heart diseases)
  5. Chest pain
  6. Gingival pain (gum pain)
  7. Headache (pain in head)
  8. Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Pruritus (severe itching of the skin)

What are the common drug interactions of Baclofen and Durezol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  4. Renal failure (kidney dysfunction)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Spinal cord abscess (pus in spinal cord)

60+:

  1. Memory impairment
  2. Disturbance in attention
  3. Oral pain
  4. Stomatitis (inflammation of mucous membrane of mouth)
  5. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  6. Activities of daily living impaired
  7. Conjunctival filtering bleb leak (blister of conjunctiva leaks)
  8. Device dislocation
  9. Hypotony of eye (low intraocular pressure (iop))
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

  1. Pain: 14 people, 30.43%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 23.91%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 19.57%
  4. High Blood Cholesterol: 7 people, 15.22%
  5. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 6 people, 13.04%
  6. Renal Cell Carcinoma (a kidney cancer): 5 people, 10.87%
  7. Neuropathy Peripheral (surface nerve damage): 4 people, 8.70%
  8. High Blood Pressure: 4 people, 8.70%
  9. Gait Disturbance: 4 people, 8.70%
  10. Stress And Anxiety: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and Durezol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Durezol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Durezol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Durezol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and difluprednate (the active ingredients of Baclofen and Durezol, respectively), and Baclofen and Durezol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: