Baclofen and Flecainide acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Flecainide acetate (flecainide acetate). Common drug interactions include dehydration among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Flecainide acetate. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Flecainide acetate?

Flecainide acetate has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 7,176 Flecainide acetate users. Check the latest studies of Flecainide acetate.

On Jul, 30, 2026

59 people who take Baclofen and Flecainide acetate together, and have interactions are studied.

Baclofen and Flecainide acetate drug interactions.

What are the common drug interactions of Baclofen and Flecainide Acetate, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Depression
Diarrhoea
Diplopia (double vision)
Dizziness
Dry eye (lack of adequate tears)
Dry skin
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)

male:

Pain
Abasia (inability to walk)
Faecal incontinence (a lack of control over passing stool)
Fall
Gait disturbance
Memory impairment
Nausea (feeling of having an urge to vomit)
Vascular dementia (vascular dementia is a general term describing problems with reasoning, planning, judgment, memory and other thought)
Hypersomnia (excessive daytime sleepiness (eds))
Acute respiratory failure

What are the common drug interactions of Baclofen and Flecainide Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiac aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure)

40-49:

Pain
Acute respiratory failure
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Aphasia (damage to the parts of the brain that control language)
Blood creatinine increased
Bone density decreased
C-reactive protein increased
Delirium (wild excitement)

50-59:

Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Speech disorder
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Vomiting
Fatigue (feeling of tiredness)
Hot flush (sudden feelings of heat)
Sleep disorder
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Fall
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Skin ulcer
Asthenia (weakness)
Depression
Diarrhoea
Dizziness
Memory impairment
Synovial cyst (cyst of joint filled with synovial fluid)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 20 people, 33.90%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 13.56%
Constipation: 7 people, 11.86%
Depression: 6 people, 10.17%
Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 8.47%
Arrhythmias (irregular heartbeat): 4 people, 6.78%
Pain: 4 people, 6.78%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 6.78%
High Blood Pressure: 4 people, 6.78%
Headache (pain in head): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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