Baclofen and Fludara drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Fludara (fludarabine phosphate). Common drug interactions include herpes zoster among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Fludara. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Fludara?

Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.

On Aug, 12, 2026

58 people who take Baclofen and Fludara together, and have interactions are studied.

What are the common drug interactions of Baclofen and Fludara, by gender? *:

female:

Herpes zoster
Infection
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Macule (a discoloured spot on the skin)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Sinusitis (inflammation of sinus)
Urinary tract infection

male:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Febrile neutropenia (fever with reduced white blood cells)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)
Atelectasis (partial or complete collapse of the lung)
Infection
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Pulmonary oedema (fluid accumulation in the lungs)
Stem cell transplant

What are the common drug interactions of Baclofen and Fludara, by age (0-1 to 60+)? *:

0-1:

Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Skin toxicity (skin damage due to toxin/poison)
Stomatitis (inflammation of mucous membrane of mouth)

2-9:

n/a

10-19:

n/a

20-29:

Febrile neutropenia (fever with reduced white blood cells)
Pneumonia

30-39:

Blood bilirubin increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)

40-49:

White blood cell count decreased
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Cardiomyopathy (weakening of the heart muscle)
Cough
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Death
Decreased appetite
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Escherichia sepsis (bacterial infection by escherichia coli)

50-59:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Cardiac arrest
Periorbital cellulitis (inflammation and infection of the eyelid and the skin surrounding the eye)
Uveitis (inflammation of the uvea)
Pneumonia
Thermal burn (burn by heat)
B-cell lymphoma (blood cancer affecting b cells)
Blood creatinine increased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Ejection fraction decreased (systolic heart failure)

60+:

Bk virus infection
Clostridial infection (infectious conditions by clostridium bacteria)
Pulmonary oedema (fluid accumulation in the lungs)
Somnolence (a state of near-sleep, a strong desire for sleep)
Hypoxia (low oxygen in tissues)
Aphasia (damage to the parts of the brain that control language)
Breast cancer
Stem cell transplant
Ascites (accumulation of fluid in the abdominal cavity)
Aspergillosis (an infection caused by a fungus called aspergillus)

What are the existing conditions these people have? *

Fever: 17 people, 29.31%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 16 people, 27.59%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 14 people, 24.14%
Cytomegalovirus Infection: 11 people, 18.97%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 10 people, 17.24%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 9 people, 15.52%
Nausea (feeling of having an urge to vomit): 9 people, 15.52%
Bone Marrow Conditioning Regimen: 9 people, 15.52%
Constipation: 8 people, 13.79%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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