Baclofen and Msm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Msm (methylsulfonylmethane). Common drug interactions include weight decreased among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Msm. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

On Jul, 20, 2026

24 people who take Baclofen and Msm together, and have interactions are studied.

What are the common drug interactions of Baclofen and Msm, by gender? *:

female:

Weight decreased
Abdominal distension
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Irritable bowel syndrome
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Vaginal infection
Vulvovaginal mycotic infection (vulvovaginal fungal infection)
Gait disturbance
Malaise (a feeling of general discomfort or uneasiness)

male:

Asthenia (weakness)
Back pain
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Distractibility (inability to sustain one's attention)
Smoke sensitivity
Temperature intolerance (inability to go in temperature)

What are the common drug interactions of Baclofen and Msm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Distractibility (inability to sustain one's attention)

40-49:

Ataxia (loss of full control of bodily movements)
Dizziness
Dysarthria (speech disorder)
Hypoaesthesia (reduced sense of touch or sensation)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Muscle rigidity (muscle stiffness)
Myalgia (muscle pain)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal discomfort

50-59:

Abdominal discomfort
Chest discomfort
Decreased appetite
Drug ineffective
Erythema (redness of the skin)
Feeling hot
Gait disturbance
Masked facies (mask like facial expression, display little facial expression)
Muscle twitching
Nausea (feeling of having an urge to vomit)

60+:

Diarrhoea
Urinary tract infection
Vaginal infection
Vulvovaginal mycotic infection (vulvovaginal fungal infection)
Asthenia (weakness)
Malaise (a feeling of general discomfort or uneasiness)
Blood urine present
Cystitis (inflammation of the wall of the bladder)
Fatigue (feeling of tiredness)
Gait disturbance

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 25.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.50%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 12.50%
Osteoporosis (bones weak and more likely to break): 2 people, 8.33%
Gait Disturbance: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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