Baclofen and Ocaliva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Ocaliva (obeticholic acid). Common drug interactions include death among females.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Ocaliva. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Ocaliva?

Ocaliva has active ingredients of obeticholic acid. eHealthMe is studying from 6,919 Ocaliva users. Check the latest studies of Ocaliva.



On Jul, 25, 2026

28 people who take Baclofen and Ocaliva together, and have interactions are studied.

Baclofen and Ocaliva drug interactions.

What are the common drug interactions of Baclofen and Ocaliva, by gender? *:

female:

  1. Death
  2. Pruritus (severe itching of the skin)
  3. Autoimmune hepatitis
  4. Back pain
  5. Cellulitis (infection under the skin)
  6. Confusional state
  7. Dizziness
  8. Drug hypersensitivity
  9. Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
  10. Fatigue (feeling of tiredness)

male:

n/a

What are the common drug interactions of Baclofen and Ocaliva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Altered state of consciousness (altered state of mind)
  2. Anaemia (lack of blood)
  3. Arthralgia (joint pain)
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Ataxia (loss of full control of bodily movements)
  7. Autoimmune hepatitis
  8. Cellulitis (infection under the skin)
  9. Confusional state
  10. Dizziness

50-59:

  1. Back pain
  2. Drug hypersensitivity
  3. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  4. Hysterectomy
  5. Stress
  6. Weight decreased
  7. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Headache (pain in head)
  10. Influenza

60+:

  1. Death
  2. Pruritus (severe itching of the skin)
  3. Vomiting
  4. Arthralgia (joint pain)
  5. Fatigue (feeling of tiredness)
  6. Gastric disorder (disease of stomach)
  7. Liver disorder (liver diseases)
  8. Drug ineffective
  9. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  10. Lower limb fracture

What are the existing conditions these people have? *

  1. Biliary Cirrhosis Primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and Ocaliva?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Ocaliva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ocaliva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ocaliva and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and obeticholic acid (the active ingredients of Baclofen and Ocaliva, respectively), and Baclofen and Ocaliva (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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