Baclofen and Tpn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Tpn (niacinamide; pyridoxine hydrochloride; tyrosine). Common drug interactions include sepsis among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Tpn. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Tpn?

Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.



On Aug, 06, 2026

13 people who take Baclofen and Tpn together, and have interactions are studied.

Baclofen and Tpn drug interactions.

What are the common drug interactions of Baclofen and Tpn, by gender? *:

female:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Vomiting
  3. Abdominal pain
  4. Abdominal pain upper
  5. Anxiety
  6. Dementia (madness)
  7. Device occlusion
  8. Dumping syndrome (a condition that can develop after surgery to remove all or part of your stomach or after surgery to bypass your stomach to help you lose weight)
  9. Eating disorder
  10. Flatulence (flatus expelled through the anus)

male:

  1. Abdominal pain
  2. Application site irritation
  3. Diarrhoea
  4. Gastrointestinal bacterial infection (infection of the stomach and intestines caused by bacteria)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Viral infection
  7. Weight increased
  8. Pyrexia (fever)

What are the common drug interactions of Baclofen and Tpn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Abdominal pain
  2. Application site irritation
  3. Diarrhoea
  4. Gastrointestinal bacterial infection (infection of the stomach and intestines caused by bacteria)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Viral infection
  7. Weight increased
  8. Pyrexia (fever)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 7 people, 53.85%
  2. Colitis (inflammation of colon): 2 people, 15.38%
  3. Gastroenteritis (inflammation of stomach and intestine): 2 people, 15.38%
  4. Tetanus (infection of the nervous system with the potentially deadly bacteria): 1 person, 7.69%
  5. Malaise (a feeling of general discomfort or uneasiness): 1 person, 7.69%
  6. Constipation: 1 person, 7.69%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.69%
  8. Hypersensitivity: 1 person, 7.69%
  9. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 1 person, 7.69%
  10. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Tpn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tpn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tpn and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and niacinamide; pyridoxine hydrochloride; tyrosine (the active ingredients of Baclofen and Tpn, respectively), and Baclofen and Tpn (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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