Baclofen and Trandate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Trandate (labetalol hydrochloride). Common drug interactions include depressed mood among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Trandate. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,664 Baclofen users. Check the latest studies of Baclofen.

What is Trandate?

Trandate has active ingredients of labetalol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,735 Trandate users. Check the latest studies of Trandate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

21 people who take Baclofen and Trandate together, and have interactions are studied.

Baclofen and Trandate drug interactions.

What are the common drug interactions of Baclofen and Trandate, by gender? *:

female:

  1. Depressed mood
  2. Lung disorder (lung disease)
  3. Pleurisy (inflammation of the pleurae, which causes pain when breathing)
  4. Pulmonary congestion (congestion in the lungs)
  5. Troponin increased
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Nausea (feeling of having an urge to vomit)
  9. Fatigue (feeling of tiredness)
  10. Pain

male:

  1. Acute myocardial infarction (acute heart attack)
  2. Hip fracture
  3. West nile viral infection
  4. Acute left ventricular failure (heart attack)
  5. Cardiac failure
  6. Cardiac failure congestive
  7. Cardiovascular disorder (heart diseases)
  8. Diplegia (paralysis of corresponding parts on both sides of the body)
  9. Multi-organ failure (multisystem organ failure)
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Baclofen and Trandate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Depressed mood
  2. Lung disorder (lung disease)
  3. Pleurisy (inflammation of the pleurae, which causes pain when breathing)
  4. Pulmonary congestion (congestion in the lungs)
  5. Troponin increased
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Bladder disorder
  9. Nausea (feeling of having an urge to vomit)
  10. Pain

50-59:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. West nile viral infection
  3. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  4. Diplegia (paralysis of corresponding parts on both sides of the body)
  5. Multi-organ failure (multisystem organ failure)

60+:

  1. Acute myocardial infarction (acute heart attack)
  2. Hip fracture
  3. Acute left ventricular failure (heart attack)
  4. Cardiac failure
  5. Cardiac failure congestive
  6. Cardiovascular disorder (heart diseases)
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

  1. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 23.81%
  2. Infection: 5 people, 23.81%
  3. Blood Pressure Abnormal: 5 people, 23.81%
  4. Poor Quality Sleep: 4 people, 19.05%
  5. Pain: 4 people, 19.05%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 19.05%
  7. Depression: 4 people, 19.05%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 19.05%
  9. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 9.52%
  10. Prostate Cancer: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and Trandate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Trandate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trandate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trandate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and labetalol hydrochloride (the active ingredients of Baclofen and Trandate, respectively), and Baclofen and Trandate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: