Baclofen and Vimovo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Vimovo (esomeprazole magnesium; naproxen). Common drug interactions include pain in jaw among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Vimovo. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

On Jul, 16, 2026

60 people who take Baclofen and Vimovo together, and have interactions are studied.

What are the common drug interactions of Baclofen and Vimovo, by gender? *:

female:

Pain in jaw
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Renal tubular necrosis (death of kidney tubules)
Retching (strong involuntary effort to vomit)
Retinal pigmentation (pigmentation of retina)
Road traffic accident
Salivary hypersecretion (excess saliva secretion)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sinusitis (inflammation of sinus)
Skin ulcer

male:

Dizziness
Chronic kidney disease
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematuria (presence of blood in urine)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)

What are the common drug interactions of Baclofen and Vimovo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Gallbladder disorder
Injection site bruising
Injection site pain
Injection site reaction
Injection site swelling
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Cholecystitis (infection of gallbladder)

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Chest discomfort
Chills (felling of cold)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dizziness
Drug ineffective
Dyspepsia (indigestion)
Fibromyalgia (a long-term condition which causes pain all over the body)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Headache (pain in head)
Gait disturbance
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Haematuria (presence of blood in urine)
Abdominal pain lower
Asthenia (weakness)
Atrioventricular block first degree (heart block first degree)
Balance disorder

60+:

Chronic kidney disease
Drug ineffective
Peripheral swelling
Balance disorder
Cataract (clouding of the lens inside the eye)
Dysarthria (speech disorder)
Dysphonia (speech disorder attributable to a disorder of phonation)
Gait disturbance
Memory impairment
Pain in extremity

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 30.00%
Pain: 12 people, 20.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 15.00%
High Blood Pressure: 8 people, 13.33%
High Blood Cholesterol: 8 people, 13.33%
Diabetes: 7 people, 11.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 10.00%
Back Pain: 5 people, 8.33%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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