Baclofen and Zoladex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Zoladex (goserelin acetate). Common drug interactions include musculoskeletal stiffness among females and hyperglycaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Zoladex. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Zoladex?

Zoladex has active ingredients of goserelin acetate. It is often used in prostate cancer. eHealthMe is studying from 13,869 Zoladex users. Check the latest studies of Zoladex.



On Jul, 13, 2026

27 people who take Baclofen and Zoladex together, and have interactions are studied.

Baclofen and Zoladex drug interactions.

What are the common drug interactions of Baclofen and Zoladex, by gender? *:

female:

  1. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  2. Swelling
  3. Abdominal pain
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Anaemia (lack of blood)
  6. Blood glucose fluctuation
  7. Bone pain
  8. Cardiomegaly (increased size of heart than normal)
  9. Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
  10. Device failure

male:

  1. Hyperglycaemia (high blood sugar)
  2. Rash
  3. Somatoform disorder (a mental disorder characterized by symptoms that suggest physical illness or injury)
  4. Vision blurred
  5. Acute myocardial infarction (acute heart attack)
  6. Anxiety
  7. Back pain
  8. Dizziness
  9. Haematochezia (passage of stools containing blood)
  10. Hip fracture

What are the common drug interactions of Baclofen and Zoladex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Haematochezia (passage of stools containing blood)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Back pain
  2. Pain
  3. Pain in extremity
  4. Anxiety
  5. Arthralgia (joint pain)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Asthenia (weakness)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Bedridden
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

50-59:

  1. Osteoporosis (bones weak and more likely to break)
  2. Osteosclerosis (an elevation in bone density)
  3. Overdose
  4. Pain
  5. Pain in extremity
  6. Pain in jaw
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Paraplegia (paralysis of the legs and lower body)
  9. Pathological fracture (broken bone caused by disease)
  10. Pelvic fracture

60+:

  1. Hyperglycaemia (high blood sugar)
  2. Rash
  3. Anaemia (lack of blood)
  4. Platelet count decreased
  5. Prostate cancer stage iii
  6. Pyrexia (fever)
  7. Secondary progressive multiple sclerosis (a stage of ms which comes after relapsing remitting ms in many cases)
  8. White blood cell count decreased
  9. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  10. Vision blurred

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 25.93%
  2. Pain: 5 people, 18.52%
  3. Stress And Anxiety: 3 people, 11.11%
  4. Seasonal Allergy (allergic condition due to certain season): 3 people, 11.11%
  5. Hypokalemia (low potassium): 3 people, 11.11%
  6. Hyperglycemia (high blood sugar): 3 people, 11.11%
  7. Rashes (redness): 2 people, 7.41%
  8. Multiple Allergies (allergy to multiple agents): 2 people, 7.41%
  9. Dry Mouth: 2 people, 7.41%
  10. Diarrhea: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and Zoladex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Zoladex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zoladex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoladex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and goserelin acetate (the active ingredients of Baclofen and Zoladex, respectively), and Baclofen and Zoladex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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