Bactrim ds and Sildenafil citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim ds (sulfamethoxazole; trimethoprim) and Sildenafil citrate (sildenafil citrate). Common drug interactions include implant site pain among females and pneumonitis among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim ds and Sildenafil citrate. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

What is Sildenafil citrate?

Sildenafil citrate has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 23,013 Sildenafil citrate users. Check the latest studies of Sildenafil citrate.

On Jul, 26, 2026

43 people who take Bactrim ds and Sildenafil citrate together, and have interactions are studied.

Bactrim ds and Sildenafil citrate drug interactions.

What are the common drug interactions of Bactrim Ds and Sildenafil Citrate, by gender? *:

female:

Implant site pain
Inflammation
Influenza
Injection site pain
Lip swelling
Lung disorder (lung disease)
Lung transplant
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

male:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pneumonia
Purpura (purplish discoloration of the skin)
White blood cell count increased
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Blood glucose increased
Bone density decreased

What are the common drug interactions of Bactrim Ds and Sildenafil Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pericarditis (inflammation of the pericardium)
Peripheral coldness
Pneumonia
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Pyrexia (fever)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Throat irritation
Fatigue (feeling of tiredness)

50-59:

Asthenia (weakness)
Dry mouth
Dyspnoea exertional (breathlessness or shortness of breath)
Haematoma (collection of blood outside the blood vessels)
Injection site bruising
Injection site discolouration
Laceration (tearing of soft body tissue)
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)
Penile haematoma (localized collection of blood outside the blood vessels on penis)

60+:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Aphthous ulcer (mouth ulcer)
White blood cell count increased
Anaemia (lack of blood)
Blood glucose increased
Glossitis (infection of tongue with soreness)
Injection site pain
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal distension

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 18 people, 41.86%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 9.30%
Multiple Myeloma (cancer of the plasma cells): 4 people, 9.30%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 6.98%
Nausea (feeling of having an urge to vomit): 3 people, 6.98%
Diabetes: 3 people, 6.98%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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