Bactrim and Alinia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim (sulfamethoxazole; trimethoprim) and Alinia (nitazoxanide). Common drug interactions include kaposi's sarcoma among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim and Alinia. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Alinia?

Alinia has active ingredients of nitazoxanide. eHealthMe is studying from 560 Alinia users. Check the latest studies of Alinia.



On Jul, 16, 2026

27 people who take Bactrim and Alinia together, and have interactions are studied.

Bactrim and Alinia drug interactions.

What are the common drug interactions of Bactrim and Alinia, by gender? *:

female:

  1. Kaposi's sarcoma (a tumour caused by human herpes virus)
  2. Diarrhoea
  3. Fatigue (feeling of tiredness)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Cholecystitis infective (infection of gallbladder capable to infect other organs)
  6. Decreased immune responsiveness
  7. Food poisoning (poison in food)
  8. Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
  9. Gastrointestinal infection (infection of stomach and intestine)
  10. Gastrointestinal viral infection (virus infection of gastrointestinal tract)

male:

  1. Confusional state
  2. Gastroenteritis cryptosporidial (inflammation of stomach and intestine caused by cryptosporidial infection)
  3. Bone loss
  4. Chronic kidney disease
  5. Emotional distress
  6. Hypotension (abnormally low blood pressure)
  7. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
  8. Pain
  9. Renal failure (kidney dysfunction)
  10. Tooth loss

What are the common drug interactions of Bactrim and Alinia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain upper

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Asthenia (weakness)
  4. Bone density decreased
  5. Bone loss
  6. Chronic kidney disease
  7. Diarrhoea
  8. Emotional distress
  9. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  10. Immunosuppression

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Bone density decreased
  4. Bone loss
  5. Cholecystitis infective (infection of gallbladder capable to infect other organs)
  6. Chronic kidney disease
  7. Decreased immune responsiveness
  8. Diarrhoea
  9. Drug resistance (reduction in effectiveness of a drug)
  10. Emotional distress

40-49:

  1. Drug hypersensitivity
  2. Liver disorder (liver diseases)

50-59:

  1. Abdominal discomfort
  2. Arthralgia (joint pain)
  3. Fatigue (feeling of tiredness)

60+:

  1. Kaposi's sarcoma (a tumour caused by human herpes virus)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Swollen tongue (swelling of tongue)
  4. Diarrhoea
  5. Abdominal distension
  6. Anaemia (lack of blood)
  7. Flatulence (flatus expelled through the anus)
  8. Gastric ulcer (stomach ulcer)
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)

What are the existing conditions these people have? *

  1. Diarrhea: 13 people, 48.15%
  2. Hiv Infection: 8 people, 29.63%
  3. Gastroenteritis Cryptosporidial (inflammation of stomach and intestine caused by cryptosporidial infection): 8 people, 29.63%
  4. Nausea And Vomiting: 7 people, 25.93%
  5. Lung Disorder (lung disease): 6 people, 22.22%
  6. Dehydration (dryness resulting from the removal of water): 6 people, 22.22%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 14.81%
  8. Amyloidosis (a tumour within which amyloid is produced): 3 people, 11.11%
  9. Cytomegalovirus Colitis (an inflammation of the colon from virus): 3 people, 11.11%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and Alinia?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bactrim and Alinia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alinia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bactrim and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alinia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim and nitazoxanide (the active ingredients of Bactrim and Alinia, respectively), and Bactrim and Alinia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: