Bactrim and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim (sulfamethoxazole; trimethoprim) and Astelin (azelastine hydrochloride). Common drug interactions include chronic kidney disease among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim and Astelin. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

On Jul, 26, 2026

92 people who take Bactrim and Astelin together, and have interactions are studied.

What are the common drug interactions of Bactrim and Astelin, by gender? *:

female:

Chronic kidney disease
Drug hypersensitivity
Nausea (feeling of having an urge to vomit)
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Hypersensitivity
Respiratory disorder (respiratory disease)
Restless legs syndrome (a powerful urge to move your legs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Abdominal pain upper
Breast pain

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dyspnoea (difficult or laboured respiration)
Chest pain
Dizziness
Dysphonia (speech disorder attributable to a disorder of phonation)
Eye pruritus (eye itching)
Eye swelling
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Ill-defined disorder

What are the common drug interactions of Bactrim and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Shoulder operation
Sinusitis (inflammation of sinus)
Abdominal pain upper
Cholecystitis acute (rapid infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Nausea (feeling of having an urge to vomit)
Vomiting

20-29:

Lung transplant
Respiratory disorder (respiratory disease)
Appendicitis (inflammation of the appendix)
Nephrolithiasis (calculi in the kidneys)

30-39:

Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hypersensitivity
Obesity (having too much body fat)
Sinusitis (inflammation of sinus)
Abnormal weight gain
Anaemia (lack of blood)
Blood iron decreased
Connective tissue disorder (any disease that has the connective tissues of the body)
Gastric haemorrhage (bleeding stomach)

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

50-59:

Fatigue (feeling of tiredness)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Laryngeal oedema (swelling of larynx)
Nausea (feeling of having an urge to vomit)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

60+:

Anxiety
Dyspnoea (difficult or laboured respiration)
Chest pain
Chills (felling of cold)
Chronic kidney disease
Dizziness
Drug hypersensitivity
Herpes zoster
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 16 people, 17.39%
Hypersensitivity: 10 people, 10.87%
Multiple Myeloma (cancer of the plasma cells): 9 people, 9.78%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 8.70%
Constipation: 7 people, 7.61%
Pain: 6 people, 6.52%
Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 6.52%
Sleep Disorder: 5 people, 5.43%
Nausea (feeling of having an urge to vomit): 5 people, 5.43%
Drowsiness: 5 people, 5.43%

* Approximation only. Some reports may have incomplete information.

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