Bactrim and Jublia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim (sulfamethoxazole; trimethoprim) and Jublia (efinaconazole). Common drug interactions include adverse drug reaction among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim and Jublia. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Jublia?

Jublia has active ingredients of efinaconazole. eHealthMe is studying from 1,780 Jublia users. Check the latest studies of Jublia.

On Jul, 15, 2026

14 people who take Bactrim and Jublia together, and have interactions are studied.

What are the common drug interactions of Bactrim and Jublia, by gender? *:

female:

Adverse drug reaction
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Asthenia (weakness)
Blood pressure increased
Blood sodium increased
Colonoscopy
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dry mouth
Fatigue (feeling of tiredness)
Feeling hot
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hip arthroplasty
Hyperkalaemia (damage to or disease of the kidney)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Leukopenia (less number of white blood cells in blood)

What are the common drug interactions of Bactrim and Jublia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Asthenia (weakness)
Blood bilirubin increased
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Upper respiratory tract infection
Vomiting

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Glomerulonephritis membranous (nephritis with inflammation of the capillary loops in the renal glomeruli)
Hypertension (high blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Pain
Renal failure (kidney dysfunction)

60+:

Diarrhoea
Weight decreased
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Dry eye (lack of adequate tears)
Fall
Fungal skin infection
Haemorrhage (bleeding)

What are the existing conditions these people have? *

Hiv Infection: 3 people, 21.43%
Pain: 3 people, 21.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
Renal Cell Carcinoma (a kidney cancer): 2 people, 14.29%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 14.29%
Peripheral Swelling: 2 people, 14.29%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 14.29%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 14.29%
Multiple Myeloma (cancer of the plasma cells): 2 people, 14.29%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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