Bactrim and Levitra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim (sulfamethoxazole; trimethoprim) and Levitra (vardenafil hydrochloride). Common drug interactions include chronic kidney disease among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim and Levitra. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Levitra?

Levitra has active ingredients of vardenafil hydrochloride. It is often used in erection problems. eHealthMe is studying from 10,392 Levitra users. Check the latest studies of Levitra.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

40 people who take Bactrim and Levitra together, and have interactions are studied.

What are the common drug interactions of Bactrim and Levitra, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)

male:

Anxiety
Emotional distress
Bone density decreased
Headache (pain in head)
Bone loss
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Tinnitus (a ringing in the ears)
Tooth loss
Drug ineffective

What are the common drug interactions of Bactrim and Levitra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood cholesterol increased
Eye disorder
Type 2 diabetes mellitus

40-49:

Scrotal abscess (pus in scrotum)
Osteoporosis (bones weak and more likely to break)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Bone pain
Chronic kidney disease
Emotional distress
Headache (pain in head)
Nephropathy (damage to or disease of a kidney)

50-59:

Fatigue (feeling of tiredness)
Chronic kidney disease
Diarrhoea
Headache (pain in head)
Abdominal discomfort
Balance disorder
Dysarthria (speech disorder)
Dysuria (painful or difficult urination)
Eye irritation
Feeling hot

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood urine present
Bone loss
Capillary disorder (capillary disease)
Defaecation urgency (a sudden compelling urge to defecate)
Diarrhoea
Dyspepsia (indigestion)
Erythema (redness of the skin)
Frequent bowel movements

What are the existing conditions these people have? *

Hiv Infection: 9 people, 22.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 20.00%
Multiple Myeloma (cancer of the plasma cells): 7 people, 17.50%
High Blood Cholesterol: 7 people, 17.50%
Depression: 5 people, 12.50%
Diabetes: 5 people, 12.50%
Pain: 5 people, 12.50%
Blood Pressure Abnormal: 4 people, 10.00%
High Blood Pressure: 4 people, 10.00%
Type 2 Diabetes: 4 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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