Bactrim and Memantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim (sulfamethoxazole; trimethoprim) and Memantine (memantine). Common drug interactions include hypoaesthesia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim and Memantine. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.

On Jul, 07, 2026

66 people who take Bactrim and Memantine together, and have interactions are studied.

Bactrim and Memantine drug interactions.

What are the common drug interactions of Bactrim and Memantine, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Injury
Intervertebral disc protrusion (spinal disc protrusion)
Lipase increased
Moaning (a low, sustained, mournful cry)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)
Neck pain
Pain in extremity
Pancreatic enzymes increased

male:

Fatigue (feeling of tiredness)
Decreased appetite
Death
Dysphagia (a condition in which swallowing is difficult or painful)
Oxygen saturation decreased
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone loss
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Bactrim and Memantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Death

10-19:

n/a

20-29:

Drug hypersensitivity
Fatigue (feeling of tiredness)

30-39:

Diarrhoea
Disease progression
Fatigue (feeling of tiredness)
Food poisoning (poison in food)
Metastases to meninges (cancer spreads to meninges)
Neoplasm progression (growth of tumour)
Pain
Sleep disorder
Vomiting
Nausea (feeling of having an urge to vomit)

40-49:

Abdominal pain upper
Alanine aminotransferase increased
Aspartate aminotransferase increased
Disease progression
Pleural effusion (water on the lungs)

50-59:

Colitis (inflammation of colon)
Dehydration (dryness resulting from the removal of water)
Vomiting

60+:

Decreased appetite
Fatigue (feeling of tiredness)
Death
Disease progression
Dysphagia (a condition in which swallowing is difficult or painful)
Oxygen saturation decreased
Vomiting
Pneumonia
Blood amylase increased
Cough

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 16 people, 24.24%
Brain Neoplasm Malignant (brain cancer tumour): 9 people, 13.64%
Memory Loss: 6 people, 9.09%
Constipation: 6 people, 9.09%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 7.58%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 7.58%
Pain: 4 people, 6.06%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 6.06%
Back Pain: 4 people, 6.06%
Blood Creatinine Increased: 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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