Bactroban and Septra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactroban (mupirocin) and Septra (sulfamethoxazole; trimethoprim). Common drug interactions include headache among females and crohn's disease among males.

The phase IV clinical study analyzes what interactions people have when they take Bactroban and Septra. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Bactroban?

Bactroban has active ingredients of mupirocin. It is often used in infection. eHealthMe is studying from 4,967 Bactroban users. Check the latest studies of Bactroban.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

40 people who take Bactroban and Septra together, and have interactions are studied.

What are the common drug interactions of Bactroban and Septra, by gender? *:

female:

Headache (pain in head)
Renal failure (kidney dysfunction)
Sinusitis (inflammation of sinus)
Anaemia (lack of blood)
Vomiting
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Ascites (accumulation of fluid in the abdominal cavity)
Back pain
Chest pain
Chills (felling of cold)

male:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Groin pain
Ileitis (inflammation of the ileum)
Inflammatory bowel disease
Irritable bowel syndrome
Multi-organ disorder (multiple organ disease)
Pain in extremity
Abdominal pain upper

What are the common drug interactions of Bactroban and Septra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Upper respiratory tract infection

10-19:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

20-29:

Anaemia (lack of blood)
Arthralgia (joint pain)
Back pain
Cardiac disorder
Chest pain
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Decreased appetite
Fatigue (feeling of tiredness)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

30-39:

Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Injury
Overdose
Wound infection staphylococcal

40-49:

n/a

50-59:

Infusion site extravasation (flow of (blood or lymph) from infusion site)
Joint swelling
Neoplasm progression (growth of tumour)
Oedema (fluid collection in tissue)
Rash
Respiratory tract infection
Sinusitis (inflammation of sinus)
Chills (felling of cold)
Drug ineffective
Headache (pain in head)

60+:

Rectal ulcer (ulcer of rectum)
Pleural effusion (water on the lungs)
Tumour pain
Nausea (feeling of having an urge to vomit)
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Dizziness
Ear pain
Fall

What are the existing conditions these people have? *

Pain: 15 people, 37.50%
Acne (skin problems that cause pimples): 10 people, 25.00%
Allergic Sinusitis: 8 people, 20.00%
Sinusitis (inflammation of sinus): 8 people, 20.00%
Constipation: 8 people, 20.00%
Gastric Ulcer (stomach ulcer): 8 people, 20.00%
Asthma: 6 people, 15.00%
Indigestion: 5 people, 12.50%
Allergic Rhinitis: 5 people, 12.50%
Back Pain: 5 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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