Belbuca and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Belbuca (buprenorphine hydrochloride) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include asthma among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Belbuca and Valacyclovir. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Belbuca?

Belbuca has active ingredients of buprenorphine hydrochloride. eHealthMe is studying from 3,022 Belbuca users. Check the latest studies of Belbuca.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On May, 25, 2026

13 people who take Belbuca and Valacyclovir together, and have interactions are studied.

Belbuca and Valacyclovir drug interactions.

What are the common drug interactions of Belbuca and Valacyclovir, by gender? *:

female:

Asthma
Dyspnoea (difficult or laboured respiration)
Throat irritation
Dysphonia (speech disorder attributable to a disorder of phonation)
Hospitalisation
Hypersensitivity
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Rash macular (small, flat red spots)
Therapeutic response decreased (less preventive response)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal impairment (severely reduced kidney function)
Spinal fracture (fracture in one of vertebrae)
Chronic kidney disease
Emotional distress
Foot fracture
Osteoporosis (bones weak and more likely to break)
Pain
Anaemia (lack of blood)

What are the common drug interactions of Belbuca and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Mobility decreased (ability to move is reduced)

50-59:

n/a

60+:

Asthma
Throat irritation
Nausea (feeling of having an urge to vomit)
Osteoporosis (bones weak and more likely to break)
Pain
Pruritus (severe itching of the skin)
Rash macular (small, flat red spots)
Therapeutic response decreased (less preventive response)
Adrenal disorder
Anaemia (lack of blood)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 4 people, 30.77%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 15.38%
Hiv Infection: 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Pain: 1 person, 7.69%
Hypersensitivity: 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Herpes Zoster: 1 person, 7.69%
Herpes Simplex (herpes simplex is a common viral infection): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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