Benlysta and Nuvigil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benlysta (belimumab) and Nuvigil (armodafinil). Common drug interactions include therapeutic response unexpected among females.

The phase IV clinical study analyzes what interactions people have when they take Benlysta and Nuvigil. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Benlysta?

Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.

What is Nuvigil?

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 23,669 Nuvigil users. Check the latest studies of Nuvigil.

On Jul, 26, 2026

34 people who take Benlysta and Nuvigil together, and have interactions are studied.

What are the common drug interactions of Benlysta and Nuvigil, by gender? *:

female:

Therapeutic response unexpected
Arthralgia (joint pain)
Depression
Feeling hot
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Migraine (headache)
Nervousness
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

male:

n/a

What are the common drug interactions of Benlysta and Nuvigil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Therapeutic response unexpected
Arthralgia (joint pain)
Obesity (having too much body fat)
Weight decreased
Depression
Eye infection
Hip fracture
Infection
Influenza like illness
Infusion site pain

40-49:

Diarrhoea
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Eructation (release of gas from the digestive tract)
Malaise (a feeling of general discomfort or uneasiness)
Menopause (end of monthly cycles in women)
Nasopharyngitis (inflammation of the nasopharynx)
Weight fluctuation
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Depression

50-59:

Drug ineffective
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Blood glucose increased
Blood pressure increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Feeling hot
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

60+:

Chest discomfort
Apathy
Pain in jaw
Skin injury
Surgery
Wheezing (a high-pitched whistling sound made while you breath)
Chest pain
Decreased interest
Depression
Diarrhoea

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 35.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 11.76%
Drowsiness: 3 people, 8.82%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.88%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 5.88%
Depression: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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