Benlysta and Phenergan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benlysta (belimumab) and Phenergan (promethazine hydrochloride). Common drug interactions include cartilage atrophy among females and altered state of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Benlysta and Phenergan. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Benlysta?

Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

On Jul, 15, 2026

53 people who take Benlysta and Phenergan together, and have interactions are studied.

Benlysta and Phenergan drug interactions.

What are the common drug interactions of Benlysta and Phenergan, by gender? *:

female:

Cartilage atrophy (cartilage extra growth)
Cartilage injury
Cold sweat
Connective tissue disorder (any disease that has the connective tissues of the body)
Constipation
Crying
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Discomfort
Dislocation of sternum

male:

Altered state of consciousness (altered state of mind)
Apnoea (suspension of external breathing)
Hyperaesthesia
Hypotension (abnormally low blood pressure)
Lung disorder (lung disease)
Lung infection
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Pyrexia (fever)
Red blood cell count decreased
Respiratory distress (difficulty in breathing)

What are the common drug interactions of Benlysta and Phenergan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Migraine (headache)
Arthropathy
Blood potassium decreased
Blood pressure decreased
Chest pain
Cold sweat
Connective tissue disorder (any disease that has the connective tissues of the body)
Dislocation of sternum
Fatigue (feeling of tiredness)
Feeling cold

30-39:

Abdominal pain
Arthralgia (joint pain)
Anxiety
Chest discomfort
Diarrhoea
Panic attack
Bone pain
Chills (felling of cold)
Dizziness
Drug ineffective

40-49:

Cough
Diarrhoea
Pain in extremity
Pyrexia (fever)
Blood pressure increased
Decreased appetite
Headache (pain in head)
Oropharyngeal pain
Abdominal pain upper
Amylase increased

50-59:

Urinary tract infection
Vertigo
Migraine (headache)
Muscle spasms (muscle contraction)
Pain in extremity
Pyrexia (fever)
Abdominal pain upper
Bradycardia (abnormally slow heart action)
Chills (felling of cold)
Depressed mood

60+:

Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Muscle atrophy (a decrease in the mass of the muscle)
Pain
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Abdominal pain lower
Altered state of consciousness (altered state of mind)
Apnoea (suspension of external breathing)
Blood lactic acid increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

* Approximation only. Some reports may have incomplete information.

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