Bentyl and Pramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bentyl (dicyclomine hydrochloride) and Pramine (imipramine hydrochloride). Common drug interactions include menometrorrhagia among females and adhesion among males.

The phase IV clinical study analyzes what interactions people have when they take Bentyl and Pramine. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

On Jul, 26, 2026

30 people who take Bentyl and Pramine together, and have interactions are studied.

What are the common drug interactions of Bentyl and Pramine, by gender? *:

female:

Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nasopharyngitis (inflammation of the nasopharynx)
Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)

male:

Adhesion
Anaemia (lack of blood)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Depression
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Drug hypersensitivity
Dysaesthesia (abnormal sensation)
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspepsia (indigestion)

What are the common drug interactions of Bentyl and Pramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Drug dependence
Anger
Exacerbation of anxiety (increase in the severity of anxiety)
Sedation
Drug effect decreased
Aggression
Anxiety
Concussion (short loss of normal brain function in response to a head injury)
Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)

40-49:

Injection site erythema (redness at injection site)

50-59:

Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Confusional state
Fall
Hepatitis c
Pain
Pneumonia
Salt craving
Urine abnormality
Back injury
Blood urine present

60+:

Ankle fracture
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiomyopathy (weakening of the heart muscle)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Dizziness
Drug hypersensitivity
Drug ineffective
Dyspepsia (indigestion)
Fall

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 30.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 16.67%
High Blood Cholesterol: 2 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 6.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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