Bentyl and Ranexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bentyl (dicyclomine hydrochloride) and Ranexa (ranolazine). Common drug interactions include dyspnoea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Bentyl and Ranexa. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.

On Jul, 24, 2026

30 people who take Bentyl and Ranexa together, and have interactions are studied.

What are the common drug interactions of Bentyl and Ranexa, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)
Abdominal pain upper
Dizziness
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Arthropathy
Balance disorder

male:

Chronic kidney disease
Rhinorrhoea (watery mucus discharge from the nose)
Dizziness
Dry skin
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Lower limb fracture
Lung disorder (lung disease)
Malignant neoplasm progression (cancer tumour came back)

What are the common drug interactions of Bentyl and Ranexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain upper
Blood glucose increased
Dizziness
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Femoral bruit (turbulent blood flow in the femoral artery)
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)

50-59:

Dyspnoea (difficult or laboured respiration)
Carotid intima-media thickness increased (increased thickness of carotid artery muscle)
Chronic kidney disease
Cough
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hepatic enzyme increased
Hypersensitivity
Hypotension (abnormally low blood pressure)
Mitral valve incompetence (inefficient heart valve)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

60+:

Chronic kidney disease
Arthralgia (joint pain)
Knee deformity (functional disability of knee)
Malaise (a feeling of general discomfort or uneasiness)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Pain
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 23.33%
Diabetes: 5 people, 16.67%
Asthma: 4 people, 13.33%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 13.33%
Pain: 4 people, 13.33%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 10.00%
Chest Pain: 3 people, 10.00%
High Blood Cholesterol: 3 people, 10.00%
Stress And Anxiety: 3 people, 10.00%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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