Bentyl and Xenical drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bentyl (dicyclomine hydrochloride) and Xenical (orlistat). Common drug interactions include diarrhoea among females and dermatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Bentyl and Xenical. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.

What is Xenical?

Xenical has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 11,722 Xenical users. Check the latest studies of Xenical.



On Jul, 26, 2026

13 people who take Bentyl and Xenical together, and have interactions are studied.

Bentyl and Xenical drug interactions.

What are the common drug interactions of Bentyl and Xenical, by gender? *:

female:

  1. Diarrhoea
  2. Dyspnoea (difficult or laboured respiration)
  3. Flatulence (flatus expelled through the anus)
  4. Pain
  5. Cholecystitis chronic (long lasting infection of gallbladder)
  6. Vomiting
  7. Abdominal distension
  8. Abdominal pain upper
  9. Defaecation urgency (a sudden compelling urge to defecate)
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Dyspnoea (difficult or laboured respiration)
  4. Erythema multiforme (a type of hypersensitivity reaction)
  5. Nausea (feeling of having an urge to vomit)
  6. Pyrexia (fever)
  7. Sore throat (pain or irritation of the throat)
  8. Steatorrhoea (presence of excess fat in faeces)
  9. Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Bentyl and Xenical, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anxiety
  2. Cholecystitis chronic (long lasting infection of gallbladder)
  3. Diarrhoea
  4. Dyspepsia (indigestion)
  5. Emotional distress
  6. General physical health deterioration (weak health status)
  7. Vomiting

20-29:

n/a

30-39:

  1. Steatorrhoea (presence of excess fat in faeces)
  2. Defaecation urgency (a sudden compelling urge to defecate)
  3. Fistula (an abnormal connection or passageway between two)
  4. Flatulence (flatus expelled through the anus)
  5. Nausea (feeling of having an urge to vomit)
  6. Abdominal pain upper
  7. Bartholin's abscess (infection of one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina)
  8. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
  9. Cholecystitis chronic (long lasting infection of gallbladder)
  10. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

40-49:

  1. Abdominal discomfort
  2. Abdominal distension
  3. Diarrhoea
  4. Faecal incontinence (a lack of control over passing stool)
  5. Faeces discoloured
  6. Flatulence (flatus expelled through the anus)
  7. Pain
  8. Steatorrhoea (presence of excess fat in faeces)

50-59:

  1. Rectal bleeding (bleeding from rectum)
  2. Steatorrhoea (presence of excess fat in faeces)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Steatorrhoea (presence of excess fat in faeces)
  3. Pain
  4. Urinary tract infection
  5. Vomiting
  6. Dehydration (dryness resulting from the removal of water)
  7. Diarrhoea
  8. Abdominal pain upper
  9. Depressed mood
  10. Diabetes mellitus non-insulin-dependent

What are the existing conditions these people have? *

  1. Depression: 2 people, 15.38%
  2. Acne (skin problems that cause pimples): 2 people, 15.38%
  3. Weight Decreased: 1 person, 7.69%
  4. Stress And Anxiety: 1 person, 7.69%
  5. Premenstrual Syndrome: 1 person, 7.69%
  6. Pain: 1 person, 7.69%
  7. Migraine (headache): 1 person, 7.69%
  8. High Blood Cholesterol: 1 person, 7.69%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Bentyl and Xenical?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bentyl and Xenical:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bentyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xenical:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bentyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xenical and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dicyclomine hydrochloride and orlistat (the active ingredients of Bentyl and Xenical, respectively), and Bentyl and Xenical (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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