Benzonatate and Clindamycin phosphate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benzonatate (benzonatate) and Clindamycin phosphate (clindamycin phosphate). Common drug interactions include pain among females and sudden death among males.

The phase IV clinical study analyzes what interactions people have when they take Benzonatate and Clindamycin phosphate. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Benzonatate?

Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 17,274 Benzonatate users. Check the latest studies of Benzonatate.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.

On Jul, 14, 2026

38 people who take Benzonatate and Clindamycin phosphate together, and have interactions are studied.

Benzonatate and Clindamycin phosphate drug interactions.

What are the common drug interactions of Benzonatate and Clindamycin Phosphate, by gender? *:

female:

Pain
Rash
Swelling face
Burning sensation
Haemoglobin decreased
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haematocrit decreased

male:

Sudden death
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Pneumonia
Rash
Thrombosis (formation of a blood clot inside a blood vessel)
Back pain
Blood sodium decreased
Cardiac failure congestive
Decreased appetite
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Benzonatate and Clindamycin Phosphate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Burning sensation
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Rash
Wisdom teeth removal
Infusion site hypersensitivity

20-29:

Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Lip swelling
Pain
Pyrexia (fever)
Swelling face
Swollen tongue (swelling of tongue)
Anaphylactic reaction (serious allergic reaction)

30-39:

Haematocrit decreased
Haemoglobin decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased
Pneumonia
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug eruption (adverse drug reaction of the skin)

40-49:

n/a

50-59:

Adverse drug reaction
Chronic kidney disease
Diabetic nephropathy (diabetic kidney disease)
Eye pain
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Proteinuria (presence of protein in the urine)
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Urinary tract disorder

60+:

Decreased appetite
Diarrhoea
Memory impairment
Nausea (feeling of having an urge to vomit)
Oral pain
Peripheral swelling
Proteinuria (presence of protein in the urine)
Renal disorder (kidney disease)
Spinal compression fracture (fracture due to spinal compression on bone)
Sudden death

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 6 people, 15.79%
Asthma: 5 people, 13.16%
Pain: 5 people, 13.16%
High Blood Pressure: 4 people, 10.53%
Insomnia (sleeplessness): 4 people, 10.53%
Immunodeficiency Common Variable: 3 people, 7.89%
Muscle Spasms (muscle contraction): 3 people, 7.89%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.89%
Anaemia (lack of blood): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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