Benzonatate and Rapaflo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benzonatate (benzonatate) and Rapaflo (silodosin). Common drug interactions include chronic kidney disease among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Benzonatate and Rapaflo. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Benzonatate?

Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 17,274 Benzonatate users. Check the latest studies of Benzonatate.

What is Rapaflo?

Rapaflo has active ingredients of silodosin. It is often used in prostate examination abnormal. eHealthMe is studying from 3,929 Rapaflo users. Check the latest studies of Rapaflo.

On Jul, 14, 2026

24 people who take Benzonatate and Rapaflo together, and have interactions are studied.

Benzonatate and Rapaflo drug interactions.

What are the common drug interactions of Benzonatate and Rapaflo, by gender? *:

female:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

male:

Renal failure (kidney dysfunction)
Pain
Multiple fractures
Renal impairment (severely reduced kidney function)
Nephropathy (damage to or disease of a kidney)
Anaemia (lack of blood)
Ankle fracture
Balance disorder
Bone pain
Calculus bladder (bladder stone)

What are the common drug interactions of Benzonatate and Rapaflo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Emotional distress
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Multiple fractures
Nephropathy (damage to or disease of a kidney)
Pain
Renal atrophy (wasting of kidney)
Renal failure (kidney dysfunction)
Rib fracture

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Ankle fracture
Balance disorder
Bone pain
Depression
Multiple fractures

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Cellulitis (infection under the skin)
Chronic hepatic failure (long lasting liver failure)
Costochondritis (chest wall pain)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 29.17%
Pain: 5 people, 20.83%
Hiv Infection: 5 people, 20.83%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 20.83%
High Blood Pressure: 4 people, 16.67%
Infection: 3 people, 12.50%
High Blood Cholesterol: 3 people, 12.50%
Prostate Cancer: 2 people, 8.33%
Multiple Allergies (allergy to multiple agents): 2 people, 8.33%
Hypersensitivity: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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