Benzonatate and Trilyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benzonatate (benzonatate) and Trilyte (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride). Common drug interactions include heart rate decreased among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Benzonatate and Trilyte. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Benzonatate?

Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 17,274 Benzonatate users. Check the latest studies of Benzonatate.

What is Trilyte?

Trilyte has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride. eHealthMe is studying from 192 Trilyte users. Check the latest studies of Trilyte.

On Jul, 14, 2026

14 people who take Benzonatate and Trilyte together, and have interactions are studied.

Benzonatate and Trilyte drug interactions.

What are the common drug interactions of Benzonatate and Trilyte, by gender? *:

female:

Heart rate decreased
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Limb discomfort (discomfort in leg)
Memory impairment
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nocturia (the need to get up in the night to urinate)
Pneumonia
Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
Presyncope

male:

Arthralgia (joint pain)
Asthenia (weakness)
Hypoxia (low oxygen in tissues)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Pneumonia
Vomiting
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Benzonatate and Trilyte, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease

60+:

Arthralgia (joint pain)
Back pain
Blood pressure decreased
Decreased appetite
Gastric infection (infection of stomach)
Haemoglobin decreased
Hypoxia (low oxygen in tissues)
Malaise (a feeling of general discomfort or uneasiness)
Abdominal pain
Actinic keratosis (skin disease due to sun exposure)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 42.86%
Pain: 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 5 people, 35.71%
High Blood Cholesterol: 4 people, 28.57%
Stress And Anxiety: 3 people, 21.43%
Nausea And Vomiting: 3 people, 21.43%
Depression: 3 people, 21.43%
Insomnia (sleeplessness): 3 people, 21.43%
Infection: 3 people, 21.43%
Inflammation: 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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