Bepreve and Epipen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bepreve (bepotastine besilate) and Epipen (epinephrine). Common drug interactions include asthma among females.

The phase IV clinical study analyzes what interactions people have when they take Bepreve and Epipen. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Bepreve?

Bepreve has active ingredients of bepotastine besilate. eHealthMe is studying from 527 Bepreve users. Check the latest studies of Bepreve.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.

On Aug, 09, 2026

22 people who take Bepreve and Epipen together, and have interactions are studied.

What are the common drug interactions of Bepreve and Epipen, by gender? *:

female:

Asthma
Sinusitis (inflammation of sinus)
Drug ineffective
Nephrolithiasis (calculi in the kidneys)
Pain
Pruritus (severe itching of the skin)
Back pain
Chest discomfort
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Arthralgia (joint pain)

male:

n/a

What are the common drug interactions of Bepreve and Epipen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chest discomfort
Dysphagia (a condition in which swallowing is difficult or painful)
Pruritus (severe itching of the skin)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Throat tightness

30-39:

n/a

40-49:

Adjustment disorder with depressed mood
Biliary dilatation
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hepatic steatosis (fatty liver disease)
Injection site reaction
Insomnia (sleeplessness)
Limb injury
Nephrolithiasis (calculi in the kidneys)
Road traffic accident

50-59:

Arthralgia (joint pain)
Asthma
Hypersensitivity
Hypertension (high blood pressure)
Lichenification (thickening and hardening of the skin)
Malaise (a feeling of general discomfort or uneasiness)
Migraine (headache)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Peripheral swelling

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 40.91%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 36.36%
Asthma: 6 people, 27.27%
Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 3 people, 13.64%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.09%
Allergic Rhinitis: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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