Bethkis and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bethkis (tobramycin) and Prilosec (omeprazole). Common drug interactions include pneumonia among females and infective pulmonary exacerbation of cystic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Bethkis and Prilosec. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Bethkis?

Bethkis has active ingredients of tobramycin. eHealthMe is studying from 2,409 Bethkis users. Check the latest studies of Bethkis.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.



On Jul, 09, 2026

32 people who take Bethkis and Prilosec together, and have interactions are studied.

Bethkis and Prilosec drug interactions.

What are the common drug interactions of Bethkis and Prilosec, by gender? *:

female:

  1. Pneumonia
  2. Productive cough
  3. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  4. Respiratory distress (difficulty in breathing)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Septic shock (shock due to blood infection)
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Sputum increased
  9. Vertebral artery hypoplasia (incomplete or arrested development of vertebral artery)
  10. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

male:

  1. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  2. Diarrhoea
  3. Blood creatinine increased
  4. Blood urea increased
  5. Bronchial haemorrhage (bleeding in bronchia)
  6. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  7. Constipation
  8. Cough
  9. Cystic fibrosis (disease of the secretary glands)
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the common drug interactions of Bethkis and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Autoimmune hepatitis
  2. Bradycardia (abnormally slow heart action)
  3. Child neglect
  4. Hypophagia (reduced food intake)
  5. Infection
  6. Pulmonary function test decreased
  7. Weight decreased

10-19:

  1. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

20-29:

  1. Acne (skin problems that cause pimples)
  2. Alanine aminotransferase increased
  3. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Bronchopulmonary aspergillosis allergic (allergic lung disorder caused by aspergillus fungi)
  6. Cough
  7. Device dislocation
  8. Fatigue (feeling of tiredness)
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

30-39:

  1. Pyrexia (fever)
  2. Acidosis (build-up of carbon dioxide in the blood)
  3. Acute respiratory distress syndrome
  4. Anaemia (lack of blood)
  5. Asthenia (weakness)
  6. Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
  7. Blood creatinine increased
  8. Blood urea increased
  9. Bronchial haemorrhage (bleeding in bronchia)
  10. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)

40-49:

n/a

50-59:

  1. Blood pressure decreased
  2. Cerebral microhaemorrhage (bleeding in brain less than 5 mm in size)
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Nausea (feeling of having an urge to vomit)
  5. Obliterative bronchiolitis (bronchiolar inflammation)
  6. Oedema peripheral (superficial swelling)
  7. Pneumonia
  8. Productive cough
  9. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  10. Respiratory distress (difficulty in breathing)

60+:

n/a

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 22 people, 68.75%
  2. Pain: 14 people, 43.75%
  3. Wheezing (a high-pitched whistling sound made while you breath): 12 people, 37.50%
  4. Asthma: 12 people, 37.50%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 12 people, 37.50%
  6. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 12 people, 37.50%
  7. Cough: 11 people, 34.38%
  8. Blood Glucose Decreased: 10 people, 31.25%
  9. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 10 people, 31.25%
  10. Nausea (feeling of having an urge to vomit): 10 people, 31.25%

* Approximation only. Some reports may have incomplete information.

Do you take Bethkis and Prilosec?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bethkis and Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bethkis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bethkis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prilosec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tobramycin and omeprazole (the active ingredients of Bethkis and Prilosec, respectively), and Bethkis and Prilosec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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