Bexarotene and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bexarotene (bexarotene) and Cyclophosphamide (cyclophosphamide). Common drug interactions include malignant neoplasm progression among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Bexarotene and Cyclophosphamide. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Bexarotene?

Bexarotene has active ingredients of bexarotene. eHealthMe is studying from 616 Bexarotene users. Check the latest studies of Bexarotene.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.



On Jul, 08, 2026

36 people who take Bexarotene and Cyclophosphamide together, and have interactions are studied.

Bexarotene and Cyclophosphamide drug interactions.

What are the common drug interactions of Bexarotene and Cyclophosphamide, by gender? *:

female:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Symptom masked
  3. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Drug ineffective
  6. Dyslipidaemia (abnormal amount of lipids)
  7. Infection
  8. Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
  9. Pain
  10. Abasia (inability to walk)

male:

  1. Drug ineffective
  2. Disease progression
  3. Paraplegia (paralysis of the legs and lower body)
  4. Pneumonia
  5. Tuberculosis (a bacterial infection by mycobacterium tuberculosis)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
  8. T-cell lymphoma (a blood cell cancer)
  9. Death
  10. Febrile neutropenia (fever with reduced white blood cells)

What are the common drug interactions of Bexarotene and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Symptom masked
  2. Drug ineffective
  3. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Disease progression
  6. Dyslipidaemia (abnormal amount of lipids)
  7. Death
  8. Hyperphagia (an abnormal appetite for food)
  9. Hypertriglyceridaemia (excess of triglycerides in the blood)
  10. Pain

40-49:

  1. Disease progression
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. General physical health deterioration (weak health status)
  4. Mycosis fungoides refractory (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin unmanageable)
  5. Abasia (inability to walk)
  6. Abscess (pus)
  7. Bacteraemia (presence of bacteria in the blood)
  8. Fatigue (feeling of tiredness)
  9. H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))
  10. Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)

50-59:

  1. Drug ineffective
  2. Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
  3. Infection
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. T-cell lymphoma (a blood cell cancer)
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  7. Pneumonia
  8. Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
  9. Tuberculosis (a bacterial infection by mycobacterium tuberculosis)

60+:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Anaplastic large cell lymphoma t- and null-cell types (t-cell or null-cell cancer, a type of blood cancer)
  3. Skin ulcer
  4. Hyperglycaemia (high blood sugar)
  5. Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
  6. Papule
  7. Paraplegia (paralysis of the legs and lower body)
  8. Pneumonia bacterial (pneumonia associated with bacterial infection)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Skin lesion

What are the existing conditions these people have? *

  1. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 12 people, 33.33%
  2. Hepatitis B: 5 people, 13.89%
  3. T-Cell Lymphoma (a blood cell cancer): 4 people, 11.11%
  4. T-Cell Lymphoma Stage Iv (one or more organs beyond the lymph nodes are affected with cancer of lymph node): 3 people, 8.33%
  5. Peripheral T-Cell Lymphoma Unspecified Stage Iv (peripheral t-cell cancer unspecified stage iv): 3 people, 8.33%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 5.56%
  7. Hepatic Function Abnormal: 2 people, 5.56%
  8. Anaplastic Large Cell Lymphoma T- And Null-Cell Types (t-cell or null-cell cancer, a type of blood cancer): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Bexarotene and Cyclophosphamide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bexarotene and Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bexarotene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bexarotene and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyclophosphamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on bexarotene and cyclophosphamide (the active ingredients of Bexarotene and Cyclophosphamide, respectively), and Bexarotene and Cyclophosphamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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