Bextra and Pulmicort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bextra (valdecoxib) and Pulmicort (budesonide). Common drug interactions include back injury among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Bextra and Pulmicort. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

What is Pulmicort?

Pulmicort has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 34,980 Pulmicort users. Check the latest studies of Pulmicort.



On Aug, 06, 2026

46 people who take Bextra and Pulmicort together, and have interactions are studied.

Bextra and Pulmicort drug interactions.

What are the common drug interactions of Bextra and Pulmicort, by gender? *:

female:

  1. Back injury
  2. Bacterial infection
  3. Blood creatine increased
  4. Blood potassium decreased
  5. Blood pressure decreased
  6. Blood triglycerides increased
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Colostomy
  9. Compression fracture (fracture due to pressure caused by injury)
  10. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

male:

  1. Renal failure (kidney dysfunction)
  2. Activities of daily living impaired
  3. Difficulty in walking
  4. Gait disturbance
  5. Cardiac failure congestive
  6. Dehydration (dryness resulting from the removal of water)
  7. Diarrhoea
  8. Hypertension (high blood pressure)
  9. Nausea (feeling of having an urge to vomit)
  10. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

What are the common drug interactions of Bextra and Pulmicort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Activities of daily living impaired
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Chest pain
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Depression
  7. Dizziness
  8. Hallucination (an experience involving the perception of something not present)
  9. Hemiplegia (paralysis of one side of the body)
  10. Influenza

40-49:

  1. Cardiomegaly (increased size of heart than normal)
  2. Chest pain
  3. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  4. Depression
  5. Depression suicidal (suicide depressive disorder)
  6. Hepatic lesion
  7. Hyperlipidaemia (presence of excess lipids in the blood)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  10. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

50-59:

  1. Anxiety
  2. Compression fracture (fracture due to pressure caused by injury)
  3. Depression
  4. Drug hypersensitivity
  5. Fall
  6. Femur fracture
  7. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  8. Pain in extremity
  9. Rib fracture
  10. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)

60+:

  1. Arthralgia (joint pain)
  2. Pain in extremity
  3. Muscle spasms (muscle contraction)
  4. Muscle twitching
  5. Nausea (feeling of having an urge to vomit)
  6. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  7. Dyspnoea (difficult or laboured respiration)
  8. Gastric disorder (disease of stomach)
  9. Intestinal functional disorder
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 8 people, 17.39%
  2. High Blood Pressure: 7 people, 15.22%
  3. Breast Cancer: 7 people, 15.22%
  4. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 13.04%
  5. Ill-Defined Disorder: 5 people, 10.87%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 10.87%
  7. Genital Haemorrhage (bleeding from genital): 4 people, 8.70%
  8. Bipolar Disorder (mood disorder): 4 people, 8.70%
  9. Peripheral Neuropathy (damage to nerves of the peripheral nervous system): 3 people, 6.52%
  10. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Bextra and Pulmicort?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bextra and Pulmicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bextra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pulmicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bextra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pulmicort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on valdecoxib and budesonide (the active ingredients of Bextra and Pulmicort, respectively), and Bextra and Pulmicort (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: