Bidil and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bidil (hydralazine hydrochloride; isosorbide dinitrate) and Ambien (zolpidem tartrate). Common drug interactions include hiatus hernia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Bidil and Ambien. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Bidil?

Bidil has active ingredients of hydralazine hydrochloride; isosorbide dinitrate. eHealthMe is studying from 520 Bidil users. Check the latest studies of Bidil.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 11, 2026

13 people who take Bidil and Ambien together, and have interactions are studied.

What are the common drug interactions of Bidil and Ambien, by gender? *:

female:

Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hydronephrosis (water inside the kidney)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Ill-defined disorder
Injury
Left ventricular dysfunction
Malaise (a feeling of general discomfort or uneasiness)

male:

Chronic kidney disease
Abdominal distension
Blood glucose decreased
Blood pressure decreased
Bradycardia (abnormally slow heart action)
Cardiac failure congestive
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Central obesity (belly fat)
Chest pain
Chills (felling of cold)

What are the common drug interactions of Bidil and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Abdominal pain upper
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Constipation
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Hypotension (abnormally low blood pressure)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Nausea (feeling of having an urge to vomit)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)

50-59:

Frequent bowel movements
Hyperphagia (an abnormal appetite for food)
Muscle spasms (muscle contraction)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Atelectasis (partial or complete collapse of the lung)
Blood cholesterol increased
Blood magnesium decreased
Blood uric acid increased
Calculus ureteric (stone in ureter)
Cardiac failure congestive

60+:

Blood potassium decreased
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Malaise (a feeling of general discomfort or uneasiness)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Pain: 4 people, 30.77%
High Blood Cholesterol: 3 people, 23.08%
Cardiac Disorder: 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
High Blood Pressure: 2 people, 15.38%
Cardiac Failure Congestive: 2 people, 15.38%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%
Depression: 2 people, 15.38%
Dizziness: 2 people, 15.38%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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