Bidil and Metronidazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bidil (hydralazine hydrochloride; isosorbide dinitrate) and Metronidazole (metronidazole). Common drug interactions include hyperplasia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Bidil and Metronidazole. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Bidil?

Bidil has active ingredients of hydralazine hydrochloride; isosorbide dinitrate. eHealthMe is studying from 520 Bidil users. Check the latest studies of Bidil.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.

On Jul, 19, 2026

12 people who take Bidil and Metronidazole together, and have interactions are studied.

Bidil and Metronidazole drug interactions.

What are the common drug interactions of Bidil and Metronidazole, by gender? *:

female:

Hyperplasia (enlargement of an organ or tissue)
Hypokinesia (decreased bodily movement)
Hypotension (abnormally low blood pressure)
Ill-defined disorder
Inflammation
Influenza like illness
Injury
Insomnia (sleeplessness)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Scrotal gangrene (death of scrotum cells)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)
Subcutaneous abscess
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Urinary tract infection
Wound abscess (pus in wound)
Acute respiratory failure

What are the common drug interactions of Bidil and Metronidazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Septic shock (shock due to blood infection)
Subcutaneous abscess
Urinary tract infection
Wound abscess (pus in wound)
Acute respiratory failure
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Chronic respiratory failure
Death

40-49:

n/a

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

60+:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Thyroid cyst
Chest discomfort
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 41.67%
Diabetes: 4 people, 33.33%
High Blood Pressure: 3 people, 25.00%
Cardiac Failure: 3 people, 25.00%
Pain: 3 people, 25.00%
Hypotension (abnormally low blood pressure): 3 people, 25.00%
High Blood Cholesterol: 3 people, 25.00%
Blood Glucose Increased: 2 people, 16.67%
Cardiac Disorder: 2 people, 16.67%
Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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